Keng-Yu Chuang

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BACKGROUND & AIMS The risks of dysplasia and esophageal adenocarcinoma (EAC) are not clear for patients with nondysplastic Barrett's esophagus (NDBE); the rate of progression has been overestimated in previous studies. We studied the incidences of dysplasia and EAC and investigated factors associated with progression of BE. METHODS The BE study is a(More)
AIM To study the angle between the circular smooth muscle (CSM) and longitudinal smooth muscle (LSM) fibers in the distal esophagus. METHODS In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis, the angles between the LSM and CSM layers were measured in 9 cadavers. The outer(More)
BACKGROUND & AIMS Data vary on the progression of low-grade dysplasia (LGD) in patients with Barrett's esophagus (BE); in patients with LGD, we investigated the incidence of high-grade dysplasia (HGD) and esophageal adenocarcinoma (EAC) and compared progression in patients with different forms of LGD (prevalent vs incident and multifocal vs unifocal). We(More)
We present the first case of telaprevir-induced pancreatitis which is summarized below. A 67-year-old Cambodian male with HTN, HCV genotype 1a/1b and viral load of 130,019 IU moved to the United States in May 2011. He had no history of drug/alcohol abuse or pancreatitis. Lisinopril 10 mg and hydrochlorthiazide (HCTZ) 25 mg daily were initiated. Alkaline(More)
Dear Editor, Recently, we performed an ERCP on a patient with the ampullary opening located within a large diverticulum and would like to comment on a similar case reported by Cappell et al. [1] in your journal. A 57-year-old Caucasian male presented with upper abdominal pain and elevated liver enzymes (ALT 58 IU, AST 55 IU, Alkaline phosphatase 162 IU and(More)
We report a case of secondary sclerosing cholangitis that manifested itself during pregnancy. A tentative diagnosis of intrahepatic cholestasis of pregnancy was considered, but after her third delivery, a liver biopsy and imaging, as well as review of past records, confirmed the diagnosis of secondary sclerosing cholangitis. Maternal and fetal outcomes of(More)
Hemoperitoneum without evidence of organ damage is a rare complication of colonoscopy. It is most frequently seen in association with splenic rupture due to traction on the splenocolic ligament. In our case, we present a 48-year-old cirrhotic man who developed peritoneal bleeding during a diagnostic colonoscopy for iron deficiency anemia. However, he was(More)
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