Ken Sekoguchi

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Although it is well known that diabetics have high mortality rates due to ischemic heart disease (IHD), controversies still exist about the severity of coronary artery disease in diabetics compared to nondiabetics. We compared coronary arteriographies of 50 diabetics with IHD to those of 50 nondiabetics with IHD. In regard to coronary risk factors,(More)
Hypercitrullinemia is a rare hereditary metabolic disorder caused by the deficiency in the activity of argininosuccinate synthetase. McMurrey et al first reported this disease in infants (1) and Saheki et al classified three types on the basis of qualitative and quantitative analysis of argininosuccinate synthetase (2). The classic neonatal and infantile(More)
Subcutaneous emphysema of the lower extremities is mostly associated with gas gangrene following trauma (1). Intraabdominal disease is a rare cause of subcutaneous emphysema of the lower extremities. This may be the result of an enteric fistula following gastrointestinal tract perforation that extends along the anatomic planes of the pelvis to the lower(More)
We describe an autopsy case of severe intracranial hemorrhage which occurred during the infusion of tissue plasminogen activator (t-PA) for acute myocardial infarction. A 75-year-old man was admitted with substernal chest pain of 3-h duration and elctro-cardiographic changes consistent with an acute inferior myocardial infarction. Physical examination was(More)
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