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  • Ken Garber
  • 2004
proposed that cancer was caused by altered metabolism— deranged energy processing—in the cell. Warburg, winner of a Nobel Prize in 1931, is now considered by many to be the greatest biochemist of the first half of the 20th century. His cancer theory, though, mostly fell on deaf ears. Altered metabolism " may be a symptom of [cancer], but not the primary(More)
VOLUME 33 NUMBER 9 SEPTEMBER 2015 NATURE BIOTECHNOLOGY autologous transplants, which would have been much more informative. “There’s only been one patient with the autologous, which is a shame,” says Pete Coffey, a stem cell researcher at University College London. “An N of one is never good, that’s for sure.” For RIKEN’s future allogeneic trial, cells will(More)
The first clinical trial of a drug’s ability to forestall Alzheimer’s disease in cognitively healthy individuals is preparing to launch. Genentech of S. San Francisco, California, the Banner Alzheimer’s Institute in Phoenix, Arizona, and the US National Institutes of Health will together spend $96 million in an international effort testing Genentech’s(More)
  • Ken Garber
  • 2011
T he March 25 approval of ipilimumab (Yervoy) by the U.S. Food and Drug Administration was a milestone for the embattled field of cancer immuno-therapy. As the first agent to increase overall survival in a phase III melanoma trial, ipilimumab appeared to vindicate the immune surveillance hypothesis of cancer first proposed in 1957. That hypothesis, which(More)