Kemal Nuri Ozerkan

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STUDY QUESTION Do the presence of endometriomas and their laparoscopic excision lead to a decrease in ovarian reserve as assessed by serum anti-Müllerian hormone (AMH) levels? SUMMARY ANSWER Both the presence and excision of endometriomas cause a significant decrease in serum AMH levels, which is sustained 6 months after surgery. WHAT IS KNOWN ALREADY(More)
OBJECTIVE This work investigates the role of glutathione S-transferase M1 (GSTM1), glutathione S-transferase T1 (GSTT1), and glutathione S-transferase P1 (GSTP1) enzymes and polymorphisms, which are found in phase II detoxification reactions in the development of cervical cancer. METHODS This study was conducted with 46 patients diagnosed with cervical(More)
PURPOSE To investigate the efficacy and safety of single-dose filgrastim administered 24 hours prior to chemotherapy in the prevention of topotecan-related myeloid suppression. METHODS No medication was given to 21 rats in group 1; 1.5 mg/m2/day topotecan was administered intraperitoneally for five days every three weeks to 21 rats in group II; a single(More)
OBJECTIVE To investigate the polymorphism rates and possible roles of glutathione-s-transferase M1, T1, and P1 gene polymorphisms in the predisposition to endometrial cancer in Caucasian women. MATERIALS AND METHODS Serum samples and medical records were collected from 53 Caucasian women with newly diagnosed endometrial cancer and 67 women of the same(More)
Single agent gemcitabine was used in recurrent epithelial ovarian cancer patients after standard treatment with debulking surgery and platin-paclitaxel based chemotherapy. Response rates and toxicity results were evaluated retrospectively. Gemcitabine was given in 1000 mg/m2 intravenous infusion over 30 minutes at 1, 8, 15 days of every 28 days. Clinical(More)
To evaluate and compare the effectiveness of magnesium sulfate (MgSO4) and mannitol in the treatment of posterior reversible encephalopathy syndrome (PRES) in eclamptic women. This retrospective analysis includes 62 eclamptic women between 22 and 40 weeks of gestation who were diagnosed with PRES in a tertiary care center. To treat neurological symptoms, 34(More)
PURPOSE The data of 11 peritoneal tuberculosis (TB) patients is discussed in an attempt to better understand this disease. METHODS Nine patients with clinical features mimicking ovarian cancer and two with infertility were evaluated retrospectively. RESULTS The mean age was 40.8 +/- 18.3 years. None had any past/family history of TB. Abdominal swelling(More)