Kelly Wink

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Dietary restriction (DR) is currently the only paradigm that has consistently extended maximal life span and reduced the onset of age-related chronic diseases in all of the nonprimate species tested. Although it is controversial, some investigators have suggested that the underlying mechanisms may be mediated by adaptations in energy expenditure. We(More)
In a comparative study 11 athletes and 11 untrained students were investigated at rest, of these 6 trained and 5 untrained individuals during exercise as well. Myocardial blood flow was measured by the argon method. Myocardial oxygen consumption, myocardial substrate uptake of glucose, lactate, and free fatty acids and cardiac output were determined by the(More)
It is shown in trained and untrained healthy individuals that the energy requirement of the physiologically hypertrophied heart is lower at rest and even more pronounced during submaximal heavy exercise compared to the non-hypertrophied state. This difference exceeds the changes which could have been anticipated by deviations in hemodynamics and total heart(More)
A male patient, aged 31 years, with a cytomegalovirus (CMV) myocarditis is described, who showed a high IgM antibody titer for cytomegalovirus infection of 1:1,024 and a rise of the titer for complement-fixing antibody from 1:< 16 to 1:256. CMV could be isolated from the urine. Investigations for other etiological factors were negative, and we assumed a(More)
  • K Wink
  • 1988
During the last 20 years there was an essential improvement in the tolerance of intravasal contrast media, leading to the nonionic low osmotic contrast media. In 26 consecutive patients with different stages of coronary heart disease the nonionic low osmolar contrast media iopamidol (Solutrast) and iopromide (Ultravist) were tested during coronary artery(More)