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Introduction: Measuring white matter perfusion using arterial spin labeling (ASL) MRI is challenging for various reasons [1]: perfusion in white matter is low compared to that in gray matter, resulting in a lower intrinsic signal to noise ratio (SNR); the relative low resolution of ASL MRI images causes partial volume effects and overestimation of white(More)
Retinal and intra-retinal layer thicknesses are routinely generated from optical coherence tomography (OCT) images, but on-board software capabilities and image scaling assumptions are not consistent across devices. This study evaluates the device-independent Iowa Reference Algorithms (Iowa Institute for Biomedical Imaging) for automated intra-retinal layer(More)
We have developed a mathematical model of the human cardiopulmonary system that is able to simulate the normal functions of the cardiovascular and pulmonary systems, as well as their coupled interactions. Included in the model are descriptions of atrial and ventricular mechanics, the hemodynamics of the systemic and pulmonic circulations, baroreflex control(More)
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