Kelly J. Cross

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A wide range of viruses, including many human and animal pathogens representing various taxonomic groups, contain genomes that are enclosed in lipid envelopes. These envelopes are generally acquired in the final stages of assembly, as viruses bud from regions of the membrane of the infected cell at which virally encoded membrane proteins have accumulated.(More)
Influenza haemagglutinin (HA) is responsible for fusing viral and endosomal membranes during virus entry. In this process, conformational changes in the HA relocate the HA(2) N-terminal 'fusion peptide' to interact with the target membrane. The highly conserved HA fusion peptide shares composition and sequence features with functionally analogous regions of(More)
The 'fusion peptides' of a group of enveloped viruses that includes influenza, paramyxo-, retro-and filo-viruses are N-terminal regions of their membrane fusion proteins generated by cleavage of non-functional precursors. For the influenza membrane fusion protein, haemagglutinin (HA), the three-dimensional structures of precursor HA, cleaved HA and(More)
The (1)H-nuclear magnetic resonance (NMR) chemical shifts of ethanol and water hydroxyl groups show a pattern change at a critical ethanol concentration. Below the critical value (20 mol% at 400 Hz), only one hydroxyl peak appears due to fast proton exchange, whereas above the critical concentration, the ethanol hydroxyl peak splits from the water peak(More)
Although vodka is a reasonably pure mixture of alcohol and water, beverage drinks typically show differences in appeal among brands. The question immediately arises as to the molecular basis, if any, of vodka taste perception. This study shows that commercial vodkas differ measurably from ethanol-water solutions. Specifically, differences in(More)
Communication and teamwork skills remain top-priority outcomes for engineering graduates. Yet researchers and educators alike know comparatively little about the teaching and learning epistemologies engineering faculty employ, or about how faculty epistemologies affect the learning mechanisms of engineering students. Our research seeks to address this gap(More)
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