Kelly F Benedict

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Over the past decade, studies applying data-driven modeling approaches have demonstrated significant contributions toward the integrative understanding of multivariate cell regulatory system operation. Here we review applications of several of these approaches, including principal component analysis, partial least squares regression, partial least squares(More)
We present a method that uses fluorescent cellular barcodes to increase the number of unique samples that can be analyzed simultaneously by microengraving, a nanowell array-based technique for quantifying the secretory responses of thousands of single cells in parallel. Using n different fluorescent dyes to generate 2(n) unique cellular barcodes, we(More)
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