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Emerging and re-emerging infectious diseases, especially those caused by drug-resistant bacteria, are a major problem worldwide. Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) appeared rapidly and unexpectedly in the United States, resulting in an epidemic caused primarily by isolates classified as USA300. The evolutionary and(More)
We reviewed 374 consecutive trauma patients over age 65 years to determine (1) if the emergency room Trauma Score (TS) could predict mortality, thereby improving ICU triage, and (2) the frequency of preventable complications in patients who died (n = 31). Fifty-two percent of deaths (n = 16) occurred in patients with TS = 15 or 16. Multiple organ(More)
BACKGROUND Tranexamic acid reduces the risk of bleeding among patients undergoing cardiac surgery, but it is unclear whether this leads to improved outcomes. Furthermore, there are concerns that tranexamic acid may have prothrombotic and proconvulsant effects. METHODS In a trial with a 2-by-2 factorial design, we randomly assigned patients who were(More)
Multiple databases provide ratings of drug-drug interactions. The ratings are often based on different criteria and lack background information on the decision making process. User acceptance of rating systems could be improved by providing a transparent decision path for each category. We rated 200 randomly selected potential drug-drug interactions by a(More)
OBJECTIVE The primary objective of this study is to compare the prevalence of phantom limb pain in New Zealand and Cambodian amputees and to assess the demographics of a sample of amputees from these two countries. DESIGN All participants were interviewed using a 12-question survey that covered demographic data and reason for amputation and assessed the(More)
Theorists of language have argued that co-speech hand gestures are an intentional part of social communication. The present study provides evidence for these claims by showing that speakers adjust their gesture use according to their perceived relevance to the audience. Participants were asked to read about items that were and were not useful in a(More)
Objective This study aimed to discover whether co-analgesia with tramadol or additional morphine was more effective for patients who still had severe pain despite being given 10 mg intravenous morphine in the post-anesthesia care unit (PACU). Methods All eligible patients were consented and recruited to the trial pre-operatively, but only a small subgroup(More)