Keith R. Pierce

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BACKGROUND Common variable immunodeficiency (CVID) is characterized by late-onset hypogammaglobulinemia in the absence of predisposing factors. The genetic cause is unknown in the majority of cases, and less than 10% of patients have a family history of the disease. Most patients have normal numbers of B cells but lack plasma cells. METHODS We used(More)
The author considers the problem of determining whether certain classes of lattice ordered groups (¿-groups) have the amalgamation property. It is shown that the classes of abelian totally ordered groups (ogroups) and abelian /-groups have the property, but that the class of ¿-groups does not. However, under certain cardinality restrictions one can find an(More)
Until recently, introductory programming classes in the Department of Computer Science, University of Minnesota, Duluth, concentrated on writing code. Not until the junior or senior year were students required to adhere to basic principles of software engineering. As might be expected, by their junior year students' bad habits, like coding while designing(More)
The urinary tract is usually culture negative despite its close proximity to microbial flora. The precise mechanisms by which the kidneys and urinary tract defends against infection is not well understood. The initial kidney cells to encounter ascending pathogens are the collecting tubule cells which consist of principal cells (PCs) that express aquaporin 2(More)
Assurance of the quality or reliability of test results is the responsibility of the laboratory and the concern of the veterinarian who uses these results in the diagnosis or treatment of animal patients. Quality assurance can be produced only by implementation and continuing maintenance of a quality control program to monitor the daily performance of the(More)
The contribution of genetic variation to urinary tract infection (UTI) risk in children with vesicoureteral reflux is largely unknown. The innate immune system, which includes antimicrobial peptides, such as the α-defensins, encoded by DEFA1A3, is important in preventing UTIs but has not been investigated in the vesicoureteral reflux population. We used(More)
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