Keith R. Davis

Learn More
Plant cells respond to low concentrations of auxin by cell expansion, and at a slightly higher concentration, these cells divide. Previous work revealed that null mutants of the alpha-subunit of a putative heterotrimeric G protein (GPA1) have reduced cell division. Here, we show that this prototypical G protein complex acts mechanistically by controlling(More)
Phenylpropanoid derivatives are a complex class of secondary metabolites that have many important roles in plants during normal growth and in responses to environmental stress. Phenylalanine ammonialyase (PAL) catalyzes the first step in the biosynthesis of phenylpropanoids, and is usually encoded by a multi-gene family. Genomic clones for three Arabidopsis(More)
Mulpuri V. Rao1, Jennifer R. Koch2 and Keith R. Davis3,∗ 1Department of Plant Biology and the Plant Biotechnology Center, 1060 Carmack Road, Ohio State University, Columbus, OH 43210, USA; 2Department of Molecular Genetics, Ohio State University and USDA Forest Service, Delaware, USA; 3Paradigm Genetics Inc., Building 2, PO Box 14528, 104 Alexander Drive,(More)
a Department of Biology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-3280 b Structural BioInformatics Core Facility, University of North Carolina School of Medicine, Chapel Hill, North Carolina 27599 c Department of Plant Research, Paradigm Genetics, Inc., Research Triangle Park, North Carolina 27709-4528 d Plant Biology(More)
An Arabidopsis cDNA clone encoding 4-coumarate:CoA ligase (4CL), a key enzyme of phenylpropanoid metabolism, was identified and sequenced. The predicted amino acid sequence is similar to those of other cloned 4CL genes. Southern blot analysis indicated that 4CL is single-copy gene in Arabidopsis. Northern blots showed that 4CL expression was activated early(More)
The role of the phytotoxin coronatine in the virulence of Pseudomonas syringae pv. tomato in Arabidopsis thaliana was evaluated by comparing symptom development, in planta bacterial multiplication, and the induction of defense-related genes in Arabidopsis plants inoculated with the coronatine-producing (Cor+) P. s. pv. tomato strain DC3000 and the(More)
Ethylene is known to influence plant defense responses including cell death in response to both biotic and abiotic stress factors. However, whether ethylene acts alone or in conjunction with other signaling pathways is not clearly understood. Ethylene overproducer mutants, eto1 and eto3, produced high levels of ethylene and developed necrotic lesions in(More)
The response of Arabidopsis thaliana land race Columbia to the bacterial pathogen Pseudomonas syringae pv. maculicola 4326 harboring cloned avirulence genes avrB and avrC from P. syringae pv. glycinea and avrA and avrD from P. syringae pv. tomato was examined. Only avrB was recognized by Columbia, as evidenced by attenuation of disease symptoms, slower(More)
Plants are exposed to various environmental stresses during their life cycle such as salt, drought and cold. Natural variation mediated plant growth adaptation has been employed as an effective approach in response to the diverse environmental cues such as salt stress. However, the molecular mechanism underlying this process is not well understood. In the(More)