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Exercise is recommended for the management of type 2 diabetes, but its effects on diabetic nephropathy (DN) are still unknown. We hypothesized that appropriate exercise improves early DN via attenuation of inflammation and oxidative damage. Type 2 diabetic KK-A(y) mice, a spontaneous DN model, underwent two different kinds of exercise (i.e., moderate and(More)
The current study aimed to examine whether the levels of TNF receptors 1 and 2 (TNFR1 and TNFR2) in serum and urine were associated with other markers of kidney injury and renal histological findings, including TNFR expression, in IgA nephropathy (IgAN). The levels of the parameters of interest were measured by immunoassay in 106 biopsy-proven IgAN patients(More)
BACKGROUND/AIMS Previous studies have shown the presence of high levels of glycoxidation and lipid peroxidation products in association with atherosclerosis in patients with end-stage kidney disease. Acetates are commonly used buffer for correcting metabolic acidosis in hemodialysis (HD) patients. Since the toxic effects of acetates are well established,(More)
Spinal evoked potentials from cervical skin surface (surface spinal evoked potentials) were measured to evaluate spinal cord function as a convenient method that precludes inserting electrodes into the epidural space, and results were compared with those of the former epidural recording method. Surface spinal evoked potentials were obtained from cervical(More)
To evaluate the function of the cervical cord and to diagnose the level and severity of cervical cord lesions in myelopathy, both segmental and conductive spinal evoked potentials (SEP) were measured in 73 patients with cervical spondylotic myelopathy and/or radiculopathy. In normal subjects, segmental SEPs consisted of two waves (R and N waves). Ascending(More)
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