Learn More
OBJECTIVE To investigate whether or not the lesions in sporadic amyotrophic lateral sclerosis (ALS) originate from a single focal onset site and spread contiguously by prion-like cell-to-cell propagation in the rostrocaudal direction along the spinal cord, as has been hypothesised (the 'single seed and simple propagation' hypothesis). METHODS Subjects(More)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease. A common characteristic of ALS pathology is cytoplasmic inclusions primarily composed of transactive response DNA-binding protein of 43 kDa (TDP-43). Production of TDP-43 in the central nervous system is strictly regulated, but it is not known whether this is also true in the skin of(More)
The aims of the present study were to investigate the shock absorption capability and force dispersion effect of mouthguard (MG) materials using load cell and film sensors. Two kinds of MG materials, ethylene vinyl acetate and polyolefin, were chosen for this study. When impact forces of approximately 5,000 N were applied on the MG materials using a round(More)
S ick sinus syndrome (SSS), or sinus node dysfunction (SND), is a common clinical disorder that was first described in 1967, 1,2 and is characterized by pathological sinus bradycardia, sinus arrest, chronotropic incompetence, and susceptibility to atrial tachycardia, especially atrial fibrillation. The syndrome comprises a variety of electrophysiological(More)
(Master's course) Kie Yoshida 2. Education Neurology is a medical specialty concerned with the diagnosis and treatment of disorders of the nervous system including the brain, spinal cord, peripheral nerves, autonomic nerves and skeletal muscles. Since the nervous system extends to the whole body and regulate all the organs, neurologists have to examine and(More)
  • 1