Keiji Kamado

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Multicentric study was conducted to evaluate the efficacy of glimepiride in the oral hypoglycemic agents therapy of type 2 diabetic patients treated with glibenclamide so far, and to claim an adequate use of this new generation sulfonylurea. In 66 diabetic outpatients, glibenclamide was switched to glimepiride. After 6 months' therapy, a significant(More)
As reported previously, we have conducted studies on causes of death among diabetic patients during the 25-year period, from 1960 to 1984, in Osaka District, Japan. We have now added the most recent 5-year data, for 1985-1989, and analyzed changes in causes of death during the entire 30-year period as a whole. The subjects studied were those for whom a(More)
A total of 23,577 death certificates mentioning diabetes, in 10,927 cases as the underlying cause and in 12,650 cases as a contributory condition, were selected from approximately 1,000,000 death certificates filed in Osaka Prefecture, Japan, during a 25-year period between 1960 and 1984. These certificates were analyzed by use of a multiple coding system.(More)
In the diagnosis of diabetic nephropathy, the patho-histological examination of a specimen obtained by autopsy or biopsy is essential. However, if an accurate substituting estimation were available, patients would not be subjected to the risk of biopsy. We have tried to estimate the patho-histological changes in glomeruli from clinico-laboratory data using(More)
OBJECTIVE To elucidate whether impairment of the myocardial free fatty acid (FFA) metabolism and small vessel abnormalities in the myocardium are etiologic or contributory factors of myocardial dysfunction in patients with NIDDM without any significant coronary artery disease. RESEARCH DESIGN AND METHODS We performed myocardial imaging with 123I-labeled(More)
To suppress the progression of diabetic microangiopathies, good control of blood glucose levels must be maintained. We examined the usefulness of glycosylated hemoglobin as an index of control of diabetes using the Markov process for the analysis of the prognosis of retinopathy. Two hundred and ninety-nine diabetics who were followed for over 3 years period(More)
There are various reports on the remission phase related to insulin response, C-peptide response, demand for exogenous insulin, and incidence and duration of remission etc. Recently, the incidence of remission was reported to be 60% in Europe and America, but these data applied to partial and complete remission. In Japan, we have no generally accepted(More)