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OBJECTIVES We carried out this cross-sectional study to explore the association between cerebral large artery lesions and leukoaraiosis in Chinese patients with stroke. The relationship between leukoaraiosis and risk factors of cerebral vascular disease was also investigated. METHODS Data were prospectively collected from patients with ischemic stroke(More)
INTRODUCTION Deep venous thrombosis (DVT) is a common complication in acute stroke. Evidence-based guidelines recommend the use of prophylactic heparins in patients with risk of DVT. We aimed to evaluate the clinical practices for DVT prophylaxis in acute stroke inpatients enrolled in a multicenter observational longitudinal study on deep venous thrombosis(More)
OBJECTIVES To determine the persistence of newly recognized abnormal glucose metabolism in patients following acute ischemic stroke and delineate the possible predictive factors for this persistence. METHODS A prospective observational study was performed. One hundred and twenty-three patients with acute first-ever ischemic stroke and no previous(More)
BACKGROUND AND PURPOSE High periprocedural complication rate is a key limitation of endovascular treatment of intracranial atherosclerotic disease (ICAD), despite potential risk reduction of recurrent stroke. Taking lessons from the Stenting and Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Arterial Stenosis (SAMMPRIS) trial,(More)
BACKGROUND AND PURPOSE The ASTRAL score was recently introduced as a prognostic tool for acute ischemic stroke. It predicts 3-month outcome reliably in both the derivation and the validation European cohorts. We aimed to validate the ASTRAL score in a Chinese stroke population and moreover to explore its prognostic value to predict 12-month outcome. (More)
BACKGROUND Intravenous (i.v.) recombinant tissue plasminogen activator (rtPA) remains the only approved therapy for acute ischemic stroke. However, the use of i.v. thrombolysis is restricted to a minority of patients by the rigid 3-h time window. Modern imaging-based selection algorithms that can identify penumbra have been proposed as methods to extend the(More)
The aim of this study was to investigate the factors affecting pre-and post-stenting head computed tomography perfusion (CTP) in patients with middle cerebral artery stenosis. A total of 25 patients with severe middle cerebral artery stenosis were enrolled. CTP was performed prior to and following stenting. Scores were allocated to the time-to-peak (TTP)(More)
In-hospital medical complications are common and strongly associated with the risk of death and dependency in stroke patients. Whether similar associations extend to stroke recurrence is unclear. We prospectively and systematically investigated whether in-hospital medical complications are associated with recurrent stroke of patients in the China National(More)
Little is known about the associations between serum uric acid (SUA) levels and atherosclerotic carotid plaque vulnerability. The aim of this study was to assess the associations of SUA levels with the prevalence of vulnerable atherosclerotic carotid plaque in a community-based cohort. In the Asymptomatic Polyvascular Abnormalities Community (APAC) study,(More)
OBJECTIVES To evaluate the role of HTPR in predicting early recurrence of ischemic events in patients with minor ischemic stroke or high-risk TIA. METHODS From January 2014 to September 2014, a single center continuously enrolled patients with minor ischemic stroke or high-risk TIA and gave them antiplatelet therapy consisting of aspirin with clopidogrel.(More)