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ADH1B*1, ADH1C*2, DRD2 (-141C Ins), and 5-HTTLPR are associated with alcoholism in Mexican American men living in Los Angeles.
- T. Konishi, Huai-Rong Luo, M. Calvillo, M. Mayo, Keh-Ming Lin, Y. Wan
- Alcoholism, clinical and experimental research
- 1 August 2004
BACKGROUND The aim of the present study was to use a candidate gene approach to identify the genetic risk factors for alcoholism in Mexican Americans residing in the Los Angeles area. The genes… Expand
CYP2B6 Polymorphisms Influence the Plasma Concentration and Clearance of the Methadone S-Enantiomer
- S. Wang, I. Ho, +18 authors Y. Liu
- Biology, Medicine
- Journal of clinical psychopharmacology
- 1 August 2011
Methadone is a racemic compound composed of the R-form and S-form enantiomers. The drug is usually used in maintenance therapy for the heroin-addicted patients. In our previous study, we found that… Expand
Predictors of the incidence and discontinuation of long-term use of benzodiazepines: a population-based study.
- Shao-You Fang, C. Chen, I-Shou Chang, E. C. Wu, C. Chang, Keh-Ming Lin
- Drug and alcohol dependence
- 1 September 2009
Long-term use of benzodiazepines (BZDs) has been linked with an array of negative health consequences and increased medical costs and social burden. In this study, we sought to investigate the… Expand
The association between dementia and long-term use of benzodiazepine in the elderly: nested case-control study using claims data.
- Chi-Shin Wu, S. Wang, I-Shou Chang, Keh-Ming Lin
- The American journal of geriatric psychiatry…
- 1 July 2009
OBJECTIVES The aim of this study was to examine the association between long-term benzodiazepines (BZDs) use and the risk of dementia. DESIGN Population-based nested case-control study of dementia.… Expand
Genetic polymorphism of cytochrome P450 2C19 in Mexican Americans: A cross‐ethnic comparative study
- Huai-Rong Luo, R. Poland, Keh-Ming Lin, Y. Wan
- Clinical pharmacology and therapeutics
- 1 July 2006
Our objectives were to investigate cytochrome P450 (CYP) 2C19 polymorphism in Mexican Americans and compare the findings with those in 4 other ethnic groups.
Differential effects of predictors on methylphenidate initiation and discontinuation among young people with newly diagnosed attention-deficit/hyperactivity disorder.
- C. Chen, H. Yeh, Kuang-Hung Chen, I-Shou Chang, E. C. Wu, Keh-Ming Lin
- Journal of child and adolescent…
- 10 June 2011
OBJECTIVE Previous population-based studies have identified factors accounting for differential utilization of psychotropic medications among young patients with attention-deficit/hyperactivity… Expand
The ADH3*2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men.
- T. Konishi, M. Calvillo, +10 authors Y. Wan
- Biology, Medicine
- Experimental and molecular pathology
- 1 April 2003
To identify the association between the polymorphisms of genes encoding alcohol metabolizing enzymes and alcoholism, the alcohol dehydrogenase 2 (ADH2), alcohol dehydrogenase 3 (ADH3), aldehyde… Expand
Factors Associated With the Diagnosis of Neurodevelopmental Disorders: A Population-Based Longitudinal Study
OBJECTIVES. We investigated the occurrence of newly diagnosed mental retardation, attention-deficit/hyperactivity disorder, and autism and sociodemographic factors associated with their distribution… Expand
Traditional Chinese Medical Beliefs and Their Relevance for Mental Illness and Psychiatry
- Keh-Ming Lin
After more than one hundred years of contact with the West and importation of Western medicine into China, traditional Chinese health beliefs and practices continue to exert important effects on the… Expand
Multidimensional assessments of impulsivity in subjects with history of suicidal attempts.
- Chi-Shin Wu, S. Liao, Keh-Ming Lin, M. M. Tseng, E. C. Wu, S. Liu
- Psychology, Medicine
- Comprehensive psychiatry
- 1 July 2009
OBJECTIVE This study aimed to examine whether subjects with history of suicidal attempts had higher impulsivity as measured by neurocognitive tests and self-report questionnaires. The… Expand