Keh-Dong Shiang

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Conversion of complex phenomena in medicine, pharmaceutical and systems biology fields to a system of ordinary differential equations (ODEs) and identification of parameters from experimental data and theoretical model equations can be treated as a computational engine to arrive at the best solution for chemical reactions, biochemical metabolic and(More)
OBJECTIVE A computational model of insulin secretion and glucose metabolism for assisting the diagnosis of diabetes mellitus in clinical research is introduced. The proposed method for the estimation of parameters for a system of ordinary differential equations (ODEs) that represent the time course of plasma glucose and insulin concentrations during glucose(More)
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