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The research presented in group 11 of the Genetic Analysis Workshop 15 (GAW15) falls into two major themes: Model selection approaches for gene mapping (both Bayesian and Frequentist); and other Bayesian methods. These methods either allow relaxation of some of the common assumptions, such as mode of inheritance, for studying complicated genetic systems, or(More)
In this paper we discuss the application of the Cluster Variation Method to the problem of genetic linkage analysis. The objective of genetic linkage analysis is to link an observed affection status (phenotype) of all individuals in a pedigree to the inheritance pattern observed certain locations on the chromosome. The Bayesian approach introduced by [7] is(More)
Contributions to Group 17 of the Genetic Analysis Workshop 15 considered dense markers in linkage disequilibrium (LD) in the context of either linkage or association analysis. Three contributions reported on methods for modeling LD or selecting a subset of markers in linkage equilibrium to perform linkage analysis. When all markers were used without(More)
We have measured the Soret coefficients of 41 out of 45 possible equimolar binary mixtures of 10 different organic solvents and found an additive rule for the heats of transport. These can, except for an undetermined offset, uniquely be assigned to the pure components. Based on their heats of transport, the fluids can be arranged according to their(More)
We present a novel grazing-incidence composite thin slab laser (CTSL) with an almost aberration-free gain medium. The laser consists of a 260-microm thin Nd:YVO4 plate that is diffusion bonded to an undoped YVO4 slab. The Nd:YVO4 plate is cooled at just one side, suppressing temperature gradients that would induce wave-front distortions in the laser field.(More)
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