Keane K. Lee

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BACKGROUND Many myocardial infarctions and strokes occur in individuals with low-density lipoprotein cholesterol levels below recommended treatment thresholds. High sensitivity C-reactive protein (hs-CRP) testing has been advocated to identify low- and intermediate-risk individuals who may benefit from statin therapy. METHODS AND RESULTS A decision(More)
BACKGROUND Lipoprotein-associated phospholipase A₂ (Lp-PLA₂) is a predictor of cardiovascular events that has been shown to vary with race. The objective of this study was to examine factors associated with this racial variation. METHODS We measured Lp-PLA₂ mass and activity in 714 healthy older adults with no clinical coronary heart disease and not(More)
Background—Many myocardial infarctions and strokes occur in individuals with low-density lipoprotein cholesterol levels below recommended treatment thresholds. High sensitivity C-reactive protein (hs-CRP) testing has been advocated to identify low-and intermediate-risk individuals who may benefit from statin therapy. Methods and Results—A decision analytic(More)
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