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It's been widely discussed in the literature that the mobility of a mobile sensor network can be used to improve the network's sensing coverage. How to efficiently manage the mobility towards a better coverage, however, remains an unanswered question. In this paper, motivated by classical dynamics that govern the movement of particles, we propose the(More)
Rubber-hand and virtual-hand illusions show that people can perceive body ownership for objects under suitable conditions. Bottom-up approaches assume that perceived ownership emerges from multisensory matching (e.g., between seen object and felt hand movements), whereas top-down approaches claim that novel body parts are integrated only if they resemble(More)
To determine if fasting would affect the intestinal expression and in vivo functional activity of PEPT1 as determined after oral dosing of the dipeptide glycylsarcosine (GlySar). Systemic exposure and tissue distribution studies were performed in wild-type and Pept1 knockout mice, under fed and fasted conditions, following both intravenous and oral doses of(More)
PURPOSE To examine the effect of intraocularly produced glucagon-like peptide-1 (GLP-1) on the survival rate of retinal ganglion cells in an optic nerve crush model. METHODS Forty-one Sprague--Dawley rats were divided into a study group (21 animals) in which 4 beads with 3000 genetically modified cells to produce GLP-1 were intravitreally implanted into(More)
Liver mass depends on one or more unidentified humoral signals that drive regeneration when liver functional capacity is diminished. Bile acids are important liver products, and their levels are tightly regulated. Here, we identify a role for nuclear receptor-dependent bile acid signaling in normal liver regeneration. Elevated bile acid levels accelerate(More)
Although progesterone was reported to be a neuroprotective agent against injuries to the nervous system, including the peripheral neuropathy, the mechanisms of its dose or timing-related effects remain unclear. Translocator protein (TSPO) is predominantly located in the mitochondrial outer membrane and has been recently implicated in modulation of several(More)
Sodium reabsorption through the epithelial sodium channel (ENaC) at the distal segment of the kidney plays an important role in salt-sensitive hypertension. We reported previously that hydrogen peroxide (H2O2) stimulates ENaC in A6 distal nephron cells via elevation of phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P3) in the apical membrane. Here we(More)
— The mobility provided by mobile ad hoc and sensor networks will facilitate new mobility-oriented services. Recent work has demonstrated that, for many issues, mobility is advantageous to network operations. This paper proposes that the need for mobility may be captured by formulating the movement of nodes as a classical dynamical system. Motivated by(More)
Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by glutamine starvation. X-box-binding protein-1u (XBP-1u) has a(More)