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It's been widely discussed in the literature that the mobility of a mobile sensor network can be used to improve the network's sensing coverage. How to efficiently manage the mobility towards a better coverage, however, remains an unanswered question. In this paper, motivated by classical dynamics that govern the movement of particles, we propose the(More)
— The mobility provided by mobile ad hoc and sensor networks will facilitate new mobility-oriented services. Recent work has demonstrated that, for many issues, mobility is advantageous to network operations. This paper proposes that the need for mobility may be captured by formulating the movement of nodes as a classical dynamical system. Motivated by(More)
BACKGROUND Bile acids are potentially toxic compounds and their levels of hepatic production, uptake and export are tightly regulated by many inputs, including circadian rhythm. We tested the impact of disrupting the peripheral circadian clock on integral steps of bile acid homeostasis. METHODOLOGY/PRINCIPAL FINDINGS Both restricted feeding, which phase(More)
Choroidal neovascularization (CNV) is the common pathological basis of irreversible visual impairment encountered in a variety of chorioretinal diseases; the pathogenesis of its development is complicated and still imperfectly understood. Recent studies indicated that delta-like ligand 4 (Dll4), one of the Notch family ligands might participate in the(More)
Autophagy is activated to maintain cellular energy homeostasis in response to nutrient starvation. However, autophagy is not persistently activated, which is poorly understood at a mechanistic level. Here, we report that turnover of FoxO1 is involved in the dynamic autophagic process caused by glutamine starvation. X-box-binding protein-1u (XBP-1u) has a(More)
PURPOSE To investigate the effect of brimonidine on the retinal ganglion cell survival in an optic nerve crush model. DESIGN Experimental animal study. METHODS Twenty-four Sprague-Dawley rats were divided into a study group of eight animals receiving intraperitoneal injections of brimonidine (1 mg/kg) and into a control group of 12 animals receiving(More)
Genomic instability, a hallmark of cancer, occurs preferentially at specific genomic regions known as common fragile sites (CFSs). CFSs are evolutionarily conserved and late replicating regions with AT-rich sequences, and CFS instability is correlated with cancer. In the last decade, much progress has been made toward understanding the mechanisms of(More)
The rubber hand illusion refers to the observation that participants perceive "body ownership" for a rubber hand if it moves, or is stroked in synchrony with the participant's real (covered) hand. Research indicates that events targeting artificial body parts can trigger affective responses (affective resonance) only with perceived body ownership, while(More)