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The purpose of this study to evaluate if vascularized iliac osteomuscular free flaps, which use simple iliac graft companied by covering the iliacus muscle in the inner cortex, is a better option for soft tissue and bone defects of the lower extremity. A retrospective review was performed on 7 consecutive patients treated with vascularized iliac(More)
OBJECTIVE To retrospectively analyze the effect of unilateral external fixators in the treatment of lower third humeral shaft fractures. METHODS From October 1997 to October 2003, 33 patients aged 15 -70 years (average 31 years) with lower third humeral shaft fractures were treated with unilateral external fixators. There were 9 spiral fractures (type(More)
OBJECTIVE To study the role of transplantation of the vascularized pedicle iliac crest for the repair of bone and soft tissue defect of lower extremity. METHODS The vascularized pedicle iliac crest was designed for the repair of bone and soft tissue defect of lower extremity according to anatomic feature of leg and foot. Skin graft was used for coverage(More)
BACKGROUND AND AIMS Toll-like receptor 4 (TLR4) contributes to ethanol-induced gastric mucosal injury. This study aimed to determine its precise role in this pathogenic state and the related signaling pathway. METHODS Ethanol-induced gastric mucosal injury models were generated in TLR4(-/-) mice (C3H/HeJ: point mutation; C57BL/10ScNJ: gene deletion),(More)
OBJECTIVE We aimed to use the meta-analysis method to assess the relationship between coffee drinking and all-cause mortality. DESIGN Categorical and dose-response meta-analyses were conducted using random-effects models. SETTING We systematically searched and identified eligible literature in the PubMed and Scopus databases. SUBJECTS Seventeen(More)
BACKGROUND Previous studies did not draw a consistent conclusion about the effects of marine-derived n-3 polyunsaturated fatty acids (PUFAs) on fasting blood level of C-reactive protein (CRP), interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α). METHODS AND FINDINGS A comprehensive search of Web of Science, PubMed, Embase and Medline (from 1950 to(More)
AIMS Propofol has demonstrated protective effects against digestive injury. Toll-like receptor-4 (TLR4) is involved in gastric mucosal injury. However, it has not yet been clarified whether propofol protects gastric mucosa from ethanol-induced injury and whether the mechanism involved is related to TLR4 activation. Therefore, this prospective study was(More)
BACKGROUND This study evaluated how the expression of miR-31 can be used to detect gastric cancer (GC) to help illuminate the role of miR-31 and RhoA in GC cells. MATERIAL AND METHODS We carried out our experiments using tissue specimens from 70 GC patients. The relative expression of miR-31 and RhoA mRNA in tissues and cells was detected by RT-PCR. The(More)