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It is widely known that, for most natural images, appropriate contrast enhancement can usually lead to improved subjective quality. Despite of its importance to image processing, contrast change has largely been overlooked in the current research of image quality assessment (IQA). To fill this void, in this paper we first report a new and dedicated(More)
We constructed a library of >10(12) unique, covalently coupled mRNA-protein molecules by randomizing three exposed loops of an immunoglobulin-like protein, the tenth fibronectin type III domain (10Fn3). The antibody mimics that bound TNF-alpha were isolated from the library using mRNA display. Ten rounds of selection produced 10Fn3 variants that bound(More)
Proper contrast change can improve the perceptual quality of most images, but it has largely been overlooked in the current research of image quality assessment (IQA). To fill this void, we in this paper first report a new large dedicated contrast-changed image database (CCID2014), which includes 655 images and associated subjective ratings recorded from 22(More)
In this paper, we propose a new no-reference (NR)/ blind sharpness metric in the autoregressive (AR) parameter space. Our model is established via the analysis of AR model parameters, first calculating the energy- and contrast-differences in the locally estimated AR coefficients in a pointwise way, and then quantifying the image sharpness with percentile(More)
PURPOSE To determine the maximum tolerated dose (MTD) of three-dimensional conformal radiation therapy (3DCRT)/intensity-modulated radiation therapy (IMRT) combined with transcatheter arterial chemoembolization for locally advanced hepatocellular carcinoma. METHODS AND MATERIALS Patients were assigned to two subgroups based on tumor diameter: Group 1 had(More)