Kazuya Matsumoto

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BACKGROUND Increased serum lipoprotein(a) [Lp(a)] is an independent risk factor for atherosclerosis. We previously reported that aspirin reduced Lp(a) production by cultured hepatocytes via the reduction of apolipoprotein(a) [apo(a)] gene transcription. METHODS We evaluated both the effect of aspirin treatment (81 mg/day) on serum Lp(a) concentrations and(More)
The abundant pigment-protein membrane complex photosystem-I (PS-I) is at the heart of the Earth's energy cycle. It is the central molecule in the "Z-scheme" of photosynthesis, converting sunlight into the chemical energy of life. Commandeering this intricately organized photosynthetic nanocircuitry and re-wiring it to produce electricity carries the promise(More)
We analyzed the effects of age and sex on habitual sleep/wake rhythm and Morningness-Eveningness scores of 2,252 subjects (6-89 years) randomly selected in Shimonoseki, Japan. Subjects were divided into 21 age groups with a matching number of men and women in each age group. The most common sleep parameter patterns by age showed a v- or inverted v-pattern(More)
To understand the sleep-wake behaviours from the fifth pre-partum week to the 15th post-partum week by the number of actigraphic activities and sleep logs were evaluated in 10 women. It was found that total sleep time shortened, sleep efficiency decreased, and wake after sleep onset (WASO) increased in the weeks immediately after delivery. Compared with(More)
BACKGROUND Imatinib used to be the only effective treatment for advanced gastrointestinal stromal tumor. However, early clinical reports have shown that sunitinib has substantial anticancer activity in patients with advanced gastrointestinal stromal tumor after failure of imatinib. METHODS Eighteen Japanese patients with advanced gastrointestinal stromal(More)
Reduction and oxidation in transition-metal oxides are keys to develop technologies related to energy and the environment. Here we report the selective topochemical reduction observed when artificial superlattices with transition-metal oxides are treated at a temperature below 300 °C with CaH(2). [CaFeO(2)](m)/[SrTiO(3)](n) infinite-layer/perovskite(More)
BACKGROUND Transurethral resection of bladder tumor (TURBT) technique has been considered the routine method for removing most bladder tumors for decades. In contrast, endoscopic submucosal dissection (ESD) is the gold-standard treatment for gastrointestinal superficial tumors. We investigated the effectiveness and applicability of a new technique for en(More)
Sleep patterns during saturation dives equivalent to a 30-m depth (pressurized condition) and habitation in a confined environment at 1 atm absolute pressure (non-pressurized condition) were studied to determine the effects of environmental pressure. Eight inexperienced divers experienced the pressurized condition of the saturation dives, and nine healthy(More)
Pancreatic cancer is the fifth leading cause of cancer death and has the lowest survival rate of any solid cancer. Endoscopic ultrasound-guided fine-needle aspiration biopsy (EUS-FNA) is currently capable of providing a cytopathological diagnosis of pancreatic malignancies with a higher diagnostic power, with a sensitivity and specificity of 85%-89% and(More)
BACKGROUND AND STUDY AIMS Specimens collected by fine needle are microscopic and contain blood; therefore, the presence of a target specimen within a sample is often difficult to confirm. Although rapid on-site evaluation (ROSE) during endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) is beneficial, many health care facilities are unable(More)