Kazutoshi Murao

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p53 prevents progression of nevi to melanoma predominantly through cell cycle regulation.

T. Terzian, Enrique C. Torchia, +11 authors Neil Box
Pigment cell & melanoma research
2010

p53 is the central member of a critical tumor suppressor pathway in virtually all tumor types, where it is silenced mainly by missense mutations. In melanoma, p53 predominantly remains wild type,… (More)

Epithelial stem cell mutations that promote squamous cell carcinoma metastasis.

Ruth Anne White, Jill M Neiman, +20 authors Xiaojing Wang
The Journal of clinical investigation
2013

Squamous cell carcinomas (SCCs) originate in stratified epithelia, with a small subset becoming metastatic. Epithelial stem cells are targets for driver mutations that give rise to SCCs, but it is… (More)

Human papillomavirus infection in Bowen disease: negative p53 expression, not p16(INK4a) overexpression, is correlated with human papillomavirus-associated Bowen disease.

Kazutoshi Murao, Rika Yoshioka, Yoshiaki Kubo
The Journal of dermatology
2014

Genital Bowen disease (BD) has been linked to the high-risk types of human papillomavirus (HPV) infection. Recently, it has been recognized that HPV also can be associated with extragenital BD. HPV… (More)

Three cases of Bowen's disease on the lower abdomen associated with high-risk types 16, 33, and 59 of human papillomavirus.

Kazutoshi Murao, Yoshiaki Kubo, Kosaku Fukuhara, Kazuya Matsumoto, Seiji Arase
Journal of the American Academy of Dermatology
2005

Strong expression of a longevity-related protein, SIRT1, in Bowen’s disease

Yasutoshi Hida, Yoshiaki Kubo, Kazutoshi Murao, Seiji Arase
Archives of Dermatological Research
2006

The class III histone deacetylase (HDAC), SIRT1, is a mammalian homologue of the Saccharomyces cerevisiae chromatin-silencing factor Sir2 that regulates longevity. SIRT1 regulates cell survival via… (More)

Ichthyosis hystrix, Curth-Macklin type: a new sporadic case with a novel mutation of keratin 1.

Yoshiaki Kubo, Yoshio Urano, +4 authors Akemi Ishida-Yamamoto
Archives of dermatology
2011

The involvement of fibroblast growth factor receptor signaling pathways in dermatofibroma and dermatofibrosarcoma protuberans.

Takeshi Ishigami, Yasutoshi Hida, Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo
The journal of medical investigation : JMI
2013

Fibroblast growth factors (FGFs) and their receptors (FGFRs) control a wide range of biological functions; however, their involvement in the pathogenesis of dermatofibroma (DF) and… (More)

Effect of Biopsy Technique on the Survival Rate of Malignant Melanoma Patients

Yutaro Yamashita, Ichiro Hashimoto, +6 authors Hideki Nakanishi
Archives of plastic surgery
2014

BACKGROUND Cutaneous malignant melanoma has a poor prognosis. The detrimental effect of incisional biopsies on the outcome of malignant melanoma has been debated. The aim of this study was to… (More)

Verrucous skin lesions on the feet in diabetic neuropathy successfully treated with topical maxacalcitol.

Kazutoshi Murao, Mika Oshima, Osamu Miyajima, Yoshiaki Kubo
European journal of dermatology : EJD
2012

Chemotherapy-induced inflammation of seborrheic keratoses due to pemetrexed treatment.

Yoshihiro Matsudate, Kazutoshi Murao, Yoshiaki Kubo
The Journal of dermatology
2017

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