Kazutaka Suzuki

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BACKGROUND Left ventricular (LV) hypertrophy and diastolic dysfunction, which are common cardiac consequences of hypertension, are modified by insulin resistance. The present study assessed the hypothesis that primary treatment of insulin resistance may reverse such cardiac changes in hypertensive patients. METHODS A total of 30 patients with essential(More)
BACKGROUND Endothelial dysfunction has been regarded as an early stage in the atherosclerotic process. Endothelial dysfunction and insulin resistance were observed in hypertensive subjects and were associated with carotid wall thickening. METHODS We examined the determinants of endothelial dysfunction including insulin sensitivity and carotid wall(More)
PURPOSE In order to analyze spontaneous blink kinematics easily and circumstantially, we developed a new method using an intelligent vision system (IVS) camera with a 1 KHz sampling rate, and evaluated the efficacy of this system. METHOD Eleven healthy male volunteers were examined after obtaining informed consent. Eyelid movements in the primary eye(More)
BACKGROUND It has been suggested that insulin resistance is involved in the impaired vascular endothelial function not only in diabetic patients but also in hypertensive patients. The present study assessed the hypothesis that primary treatment of insulin resistance may reverse endothelial dysfunction in hypertensive subjects. METHODS Fifteen nondiabetic(More)
Insulin resistance and hyperinsulinemia have been observed in over 70% of the nonobese, nondiabetic subjects with essential hypertension (HT). Alpha-1 blockers, ACE-antagonists, long-acting Ca blockers including nifedipine CR, some form of beta-blockers, tilisolor, which is reported to increase blood flow, improve insulin sensitivity when blood pressure is(More)
Pregnancies with fetuses affected with the Bartter syndrome, an autosomal recessive disorder of hyperreninism and hyperaldosteronism, are complicated by early onset of polyhydramnios which results in preterm deliveries. We have assessed biochemical changes in amniotic fluid and the mother's blood with a view to early diagnosis. Aldosterone levels of both(More)
BACKGROUND The mechanism of alcohol-induced syncope is unknown. METHODS AND RESULTS Head-up tilt tests (HUT: upright at 80 degrees for 30 min) were performed before and after alcohol consumption in 25 patients with unexplained syncope after drinking alcohol. Plasma levels of epinephrine (P-E) and norepinephrine (P-NE) were measured in a supine position(More)
Tolvaptan is an oral vasopressin type 2 receptor antagonist that can be used for heart failure patients with hyponatremia or symptomatic congestion. Although the effects of tolvaptan in adults have been well documented, only limited information is available in children. The case of a neonate with congestive heart failure complicated with chylothorax after(More)
Basic autonomic nervous function was evaluated in patients with neurocardiogenic syncope (NCS). Atropine, isoproterenol, propranolol, phenylephrine, and phentolamine were administered successively, and parasympathetic nerve activity and beta- (and alpha-) activity, sensitivity, and secretion of the sympathetic nerve were determined in patients with NCS and(More)
INTRODUCTION Parkinson's disease (PD) patients often have a blinking abnormality. In this study, we examined the kinematic features of spontaneous blinking in 65 PD patients and 62 healthy controls by a new research method utilizing an intelligent vision sensor camera prototype with a 1kHz sampling rate. METHODS Spontaneous blinks were measured by use of(More)