Kazuo Hino

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Cigarette smoke induces skeletal muscle wasting by a mechanism not yet fully elucidated. Branched-chain amino acids (BCAA) in the skeletal muscles are useful energy sources during exercise or systemic stresses. We investigated the relationship between skeletal muscle wasting caused by cigarette smoke and changes in BCAA levels in the plasma and skeletal(More)
To compare oral rehydration solution (ORS) with saline infusion for preventing contrast-induced nephropathy (CIN) in a rat model. Adult male Sprague–Dawley rats (310–360 g) received intravenous indomethacin (10 mg/kg), N G-nitro-l-arginine methyl ester (10 mg/kg), and iohexol (10 mL/kg) to induce acute contrast-induced renal injury (CIN group); control rats(More)
Currently, outpatient cancer chemotherapy has been commonly performed in Japan. However, chemotherapies using cisplatin( CDDP)are seldom given to outpatients because they require vigorous hydration to reduce CDDP-induced nephrotoxicity. In this study, we investigated the protective effect of oral rehydration solution(ORS)against CDDP-induced nephrotoxicity,(More)
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