Kazunori Yamaguchi

Learn More
Several recent studies have revealed that microRNAs (miRNAs) have a role in carcinogenesis and cancer development, and that it is stably detectable in plasma/serum. The aim of this study was to test whether miR‑483-3p as well as miR‑21 could be plasma biomarkers for PDAC. The plasma samples were obtained from three groups including 32 pancreatic ductal(More)
Recent improvements to Monte Carlo tree search have produced strong computer Go programs. This paper presents a method of measuring the accuracy of Monte Carlo tree search in game programming. We use the win percentage of positions in a large database of game records as a benchmark and compare the win probability obtained by simulations with the benchmark.(More)
This paper presents a method of evaluating game tree search methods including standard min-max search with heuristic evaluation functions and Monte Carlo tree search, which recently achieved drastic improvements in the strength of Computer Go programs. The basic idea of this paper is to use an averaged win probability of positions having similar evaluation(More)
Plasma membrane-associated sialidase (Neu 3), which specifically hydrolyzes gangliosides, is relatively abundantly present in the nervous system. To understand the role of Neu 3 in neuronal differentiation, we studied the relationship between neurite outgrowth and Neu 3 expression in human neuroblastoma NB-1 cells. The expression of Neu 3 in NB-1 cells(More)
The long non-coding RNA HOTAIR has been reported to be a poor prognostic biomarker in a variety of malignant tumors. However, little is known about the association of HOTAIR with gastric cancer. We examined the expression of HOTAIR in 68 gastric cancer samples using quantitative real-time RT-PCR and analyzed its correlation with the clinical parameters. The(More)
Synapses between taste receptor cells and primary sensory afferent fibers transmit the output signal from taste buds to the central nervous system. The synaptic vesicle cycle at the synapses involves vesicle docking, priming, fusion, endocytosis, and recycling. Many kinds of synaptic vesicle proteins participate in synaptic vesicle cycles. One of these,(More)
The neurons in the trigeminal ganglion (TG) are surrounded by satellite glial cells (SGCs), which passively support the function of the neurons, but little is known about the interactions between SGCs and TG neurons after peripheral nerve injury. To examine the effect of nerve injury on SGCs, we investigated the activation of SGCs after neuronal damage due(More)
Focused crawlers are considered as a promising way to tackle the scalability problem of topic-oriented or personalized search engines. To design a focused crawler, the choice of strategy for prioritizing unvisited URLs is crucial. In this paper, we propose a method using a decision tree on anchor texts of hyperlinks. We conducted experiments on the real(More)