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It is known that the clock-period can be shorter than the maximum of signal-delays between registers if the clock arrival time to each register is properly scheduled. The algorithm to design an optimal clock-schedule was given. In this paper, we propose a clock-tree routing algorithm that realizes a given clock-schedule using the Elmore-delay model.(More)
BACKGROUND Recent studies have demonstrated that podocyte injury, which results in proteinuria, leads to tubulointerstitial fibrosis. Although some studies have revealed that vitamin D administration protects renal structure and function in mesangial cell proliferative and/or excessive matrix productive models, the effects of vitamin D on podocyte injury(More)
SUMMARY It is known that the clock-period can be shorter than the maximum of signal-delays between registers if the clock arrival time to each register is properly scheduled. The algorithm to design an optimal clock-schedule was given. In this paper, we propose a clock-tree routing algorithm that realizes a given clock-schedule using the Elmore-delay model.(More)
The combination of serum 25-hydroxyvitamin D (25D) and fibroblast growth factor 23 (FGF23) levels predict hard renal outcomes in patients with chronic kidney disease (CKD), independent of classical markers of mineral and bone disorders, including serum phosphorus, parathyroid hormone, 1,25-dihydroxyvitamin D levels, and active vitamin D therapy. In a(More)
BACKGROUND Renal prognosis of IgA nephropathy (IgAN) is affected by environmental and genetic factors. Other studies demonstrated that some atherosclerotic disease-related genes were significantly associated with renal prognosis. METHODS The Polymorphism REsearch to DIstinguish genetic factors Contributing To progression of IgAN (PREDICT-IgAN) was a(More)
Determination of the EEG sleep stages by clinicians is a time consuming task, because of a great amount of record obtained during one night. Therefore, an effective computer technique for an automatic processing EEG is strongly desired. We tried to make a real-time automatic determination system of human sleep EEG stages by a micro-computer. The system is(More)
MM et al. Toxicity of sunitinib plus bevacizumab in renal cell carcinoma. Renal thrombotic micro-angiopathy caused by anti VEGF-antibody treatment for metastatic renal-cell carcinoma. A, Nadasdy T et al. Proteinuria in a patient receiving anti-VEGF therapy for metastatic renal cell carcinoma. Haemorrhagic shock induced by subcutaneous insulin injection(More)
S-1 and cisplatin are used as one of the first-line chemotherapies for gastric cancer in Japan. The plasma concentration of 5-fluorouracil (5-FU) is increased in patients with renal dysfunction because gimeracil in S-1 inhibits the degradation of 5-FU and about 50% of gimeracil is excreted in the urine. We describe a 35-year-old man with acute kidney injury(More)
Recently, collaborative filtering is proposed as an information gathering technology of the WWW in the network. Collaborative filtering is a technology that recommends information on the Web page for an arbitrary user who wants to acquire recommendation information based on many users' evaluation and retrieval histories. In this paper, the bookmark shared(More)
Many computing systems have been developed and applied to the sleep studies. The most famous system is EEG sleep stage determination system. It becomes possible to process the PSG data during one night in a few minutes by these systems. We also have been studying for such system and analyzing method of EEG. This paper presents the feature extraction and(More)