Kazunari Furusawa

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A new task for the analysis of drug effects on the cognitive function in mice was investigated using a 4-arm maze with three selectable arms. Each trial consisted of a forced run either to the right or left arm containing a food pellet, which was changed for each trial, followed by a free-choice run after a delay (0-120 sec). The correct response was to(More)
Interleukin-6 (IL-6) is produced by contracting skeletal muscles and then released into the circulation and considered to mediate the health benefits of exercise against chronic diseases. Individuals with spinal cord injury (SCI) are reported to be at higher risk of developing metabolic diseases. We investigated the IL-6 responses to 20-min arm crank(More)
Effects of diazepam, pentobarbital, morphine, ethanol, caffeine, and nicotine on the conflict behavior established under a MULT FR 20/FR 20 punishment schedule of food reinforcement were investigated in Mongolian gerbils. Fourteen out of 17 gerbils learned lever-press response for food within 15 sessions of training under FR 20 schedule. Although high(More)
Effects of psychotropic drugs on lever-press and shuttle discrete avoidance responses were investigated by the cumulative-dosing procedure in mice. For cumulative determination, doses of drugs were given 3 times every 1 h within the same session. As a control, the intermittent-dosing procedure in which a single dose was given twice a week was also tested.(More)
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