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Alkaloids from the seeds of Peganum harmala showing antiplasmodial and vasorelaxant activities
TLDR
Quinazoline alkaloid, vasicinone, showed a vasorelaxant activity against phenylephrine-induced contraction of isolated rat aorta and a moderate in vitro antiplasmodial activity against Plasmodium falciparum.
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Studies on the constituents from the fruits of Phaleria macrocarpa
From the fruits of Phaleria macrocarpa, icariside C3 (1), phalerin (2), and mangiferin (3) were isolated and their structures were identified on the basis of spectroscopic data. Icariside C3 (1)…
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Vasorelaxant effect of FR900359 from Ardisia crenata on rat aortic artery
TLDR
The results suggest that the vasorelaxant effect of FR900359 is mediated through the increased release of NO from endothelium-intact aortic cells at low concentrations, and can be attributed to inhibitory effects on voltage-dependent Ca2+ channel- and receptor-operated Ca2- channel-dependentCa2+ influx at high concentrations.
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Vasorelaxant activity of indole alkaloids from Tabernaemontana dichotoma
TLDR
The methanol extract from bark of Tabernaemontana dichotoma showed vasorelaxant activity on rat aorta and mechanism of action of 10-methoxyaffinisine (2), cathafoline (4), and alstonisine (7) was clarified.
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Synthesis and structure-activity relationships of cassiarin A as potential antimalarials with vasorelaxant activity.
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Vasorelaxant effects of macrocyclic bis(bibenzyls) from liverworts.
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Lancifoliaine, a New Bisbenzylisoquinoline from the Bark of Litsea lancifolia
TLDR
N-Allyllaurolitsine (2) showed a moderate vasorelaxant activity on isolated rat aorta and the alkaloidal structures were elucidated by means of high field 1D- and 2D-NMR IR, UV, and LCMS-IT-TOF spectral data.
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Vasorelaxant effects on rat aortic artery by two types of indole alkaloids, naucline and cadamine
TLDR
Results suggested that the vasorelaxant effect of cadamine is partly mediated through the increased release of NO from endothelial cells, which was attributed to inhibition of both VDC- and ROC-dependent Ca2+ influx.
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Alstilobanines A—E, New Indole Alkaloids from Alstonia angustiloba.
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Complanadine F, a novel dimeric alkaloid from Lycopodium complanatum
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