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As is known from various animal models, the spread of agents causing transmissible spongiform encephalopathies (TSE) after peripheral infection affects peripheral nerves before reaching the central nervous system (CNS) and leading to a fatal end of the disease. The lack of therapeutic approaches for TSE is partially due to the limited amount of information(More)
In Bacillus subtilis the physiological consequences of depriving lipoteichoic acid and wall teichoic acid of D-alanine ester were analysed using insertional inactivation of the genes of the dlt operon. Mutant strains which lacked positively charged o-alanine ester in teichoic acids bound more positively charged cytochrome c than other strains. These mutant(More)
In its natural habitat, the soil bacterium Bacillus subtilis often has to cope with fluctuating osmolality and nutrient availability. Upon nutrient depletion it can form dormant spores, which can revive to form vegetative cells when nutrients become available again. While the effects of salt stress on spore germination have been analyzed previously,(More)
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