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  • Kayo Umekawa, Haruhiko Hasegawa, Yuichiro Tsutsumi, Kei Sato, Yasuo Matsumura, Noriko Ohashi
  • Chemistry, Medicine
  • Japanese journal of pharmacology
  • 2000
  • We describe the pharmacological characteristics of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl-1-phenyl-1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt). SM-19712 inhibitedContinue Reading
    Effects of SM-19712 (4-chloro-N-[[(4-cyano-3-methyl- 1-1-phenyl- 1H-pyrazol-5-yl)amino]carbonyl] benzenesulfonamide, monosodium salt), a novel endothelin converting enzyme (ECE) inhibitor, onContinue Reading
  • Kazuto Yamazaki, Hirohiko Hasegawa, Kayo Umekawa, Yasuyuki Ueki, Naohito Ohashi, Masaharu Kanaoka
  • Chemistry, Medicine
  • Bioorganic & medicinal chemistry letters
  • 2002 (First Publication: 1 May 2002)
  • A novel non-peptidyl endothelin converting enzyme inhibitor was obtained through a pharmacophore analysis of known inhibitors and three-dimensional structure database search. Analogues of the newContinue Reading