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The purpose of the present study was to investigate GSTM1 and GSTT1 genotypes by using multiplex polymerase chain reaction (PCR) in patients with laryngeal squamous cell carcinoma (LSCC). The genotypes of 110 patients with LSCC and of 197 healthy subjects as the control group were determined by PCR analysis for GSTM1 and GSTT1 genes. Results showed that(More)
OBJECTIVES To evaluate the glutation-S-transferase (GST) polymorphisms (GSTM1 and GSTT1) in nasal polyposis (NP). METHODS The study population consisted of 102 unrelated healthy individuals and 98 patients with NP (67 without asthma, 31 with asthma). Genotyping of the polymorphism in the GSTM1 and GSTT1 genes was performed using the multiplex polymerase(More)
CONCLUSIONS Our results support the proposition that hyaluronic acid (HA) provides a moist wound-healing environment to aid in the healing process of tympanic membrane perforation. A single MeroGel administration can be effective as well as daily topical HA application in the treatment of tympanic membrane perforations. A single application of esterified HA(More)
OBJECTIVES/HYPOTHESIS We aimed to evaluate the effectiveness of topical intranasal fluorescence application together with high-resolution computed tomography and magnetic resonance imaging and/or magnetic resonance cisternography for the preoperative diagnosis of cerebrospinal fluid (CSF) leakage and for intraoperative localization of CSF fistulas. We also(More)
OBJECTIVES An unusual case of hydatid disease is reported. Review of the pertinent literature did not reveal any hydatid disease located simultaneously in both the intracranial and submandibular glands. This is the first case with hydatid disease occurring in both locations at the same time. STUDY DESIGN The case of an 18-year-old is presented; the(More)
PURPOSE In this computer-based study, finite element analysis (FEA) was performed to assess the most suitable shape and fixation technique for a certain type of mandible fracture at corpus. MATERIALS AND METHODS A model of the mandible was prepared using computed tomography (CT) scans. The CT scans were transferred and converted to the finite element(More)
Submandibular gland mucocele should be remembered in the differential diagnosis of swelling at the submandibular triangle. In the cystic lesion of the submandibular area, the biochemical analysis of aspirated material for amylase should be performed. The cases with submandibular gland mucocele should be treated by removing the lesion with both the(More)
OBJECTIVES The purpose of the study is to investigate whether there is any association between pharyngeal reflux and adenoid hyperplasia by using 24-h esophageal pH monitoring with a dual probe in children. METHODS The study group consisted of 30 children with adenoid hyperplasia, and the control group consisted of 12 healthy children, studied(More)
OBJECTIVE To investigate the incidence of chromosome 8 aneuploidy in acquired cholesteatoma. MATERIAL AND METHOD Cholesteatoma tissue and postauricular skin as a control were surgically obtained from 12 patients with acquired cholesteatoma. Fluorescence in situ hybridization (FISH) analysis using a chromosome 8-specific alpha-satellite DNA probe was(More)
OBJECTIVES/HYPOTHESIS The aim of the present study was to investigate the relationship between the eustachian tube (ET) and petrous internal carotid artery (ICA) in whole-mount human temporal bone specimens. STUDY DESIGN Descriptive study. METHODS Histologically prepared serial sections of 10 adult temporal bones were included in the study. Five(More)