Kaushik Sarkar

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The toxic effect of Bisphenol A (BPA) on heart ventricular function has not been reported till date. So the present study was undertaken to examine the effect of BPA on ventricular function in rat models. BPA (50mg/kgBW/day) was administered for 20 and 30 days by oral-gavage. The rats were sacrificed by cervical dislocation on 24 th hour after last(More)
An antibody format, termed Fab-dsFv, has been designed for clinical indications that require monovalent target binding in the absence of direct Fc receptor (FcR) binding while retaining substantial serum presence. The variable fragment (Fv) domain of a humanized albumin-binding antibody was fused to the C-termini of Fab constant domains, such that the VL(More)
CONTEXT Anemia is a major contributor to morbidity and mortality among women of reproductive age. Progress toward reducing the burden of anemia has been little despite efforts through decades. AIMS We conducted this study to unearth the microlevel determinants of anemia among women of reproductive age. SETTINGS AND DESIGN This qualitative study was(More)
The aim of the present study was to examine the effects of MSG on the function of the uterus. We have observed significant degenerative changes in the endometrial and myometrial layers of the uterus in MSG exposed rats in a dose dependent manner compared to wall structure of the uterus of control rats. To elucidate the causes of MSG induced necrosis of the(More)
Ureteral tumors are rare and benign tumors are even rarer. Most of such tumors are diagnosed after nephroureterectomy assuming a malignant lesion, but with modern technological advancements like contrast enhanced CT scan or MR urography and ureteroscopic biopsy, benign nature of such tumors can be established preoperatively with an aim to preserve the renal(More)
We report here the toxic effects of Bisphenol A (BPA) on the function of duodenum in vitro of rats. We found significant depression of amplitude (in 20 days exposure groups) and frequency of contraction of duodenum (in 30 days exposure groups). We also observed a significant increase in acetylcholinesterase (AChE) activity in duodenal tissues in both the(More)
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