Katsuyuki Okamoto

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Patients with glioma(which constitute 33% of all brain tumor cases) still have a poor prognosis, especially in the case of malignant(anaplastic astrocytoma and glioblastoma). This poor prognosis is related to the fact that malignant glioma cells aggressively infiltrate into normal brain tissues, making total removal of the tumor impossible. The median(More)
We have previously shown that anacardic acid has an uncoupling effect on oxidative phosphorylation in rat liver mitochondria using succinate as a substrate (Life Sci. 66 (2000) 229-234). In the present study, for clarification of the physicochemical characteristics of anacardic acid, we used a cyanine dye (DiS-C3(5)) and 9-aminoacridine (9-AA) to determine(More)
A 70-year-old woman was admitted because of depression and abnormal involuntary movements of her left extremities. Six months before the admission, she developed left hemiparesis caused by right thalamic hemorrhage. On neurological examination, she had mild motor and sensory hemiparesis on the left side. She showed recurrent depression each other days with(More)
The structures of two new chlorine-containing C6-C3 compounds isolated from the woods of Illicium tashiroi have been established as 2(R)-12-chloro-2,3-dihydroillicinone E (1) and 12-chloroillicinone E (2) by X-ray crystallographic analysis and spectroscopic data, respectively. Compound 1 has been found to significantly increase ChAT activity in culture of(More)
A case report is presented here. A 33-year-old female who had been medicated with Chinese medicine showed a typical psychomotor status which conformed to all items of Heintel's and Treiman and Delgado-Escueta's diagnostic criteria of psychomotor status. When she was 33 years old in the 34th week of pregnancy on April 11, 1981, she was found to be in an(More)
A case report of psychomotor status was presented. A 51-year-old male caught a cold and had a high fever at the end of September, 1979. On October 7th, he had a visual hallucination followed by a generalized seizure. After hospitalization he went through several fits of automatism. On October 15th, he was seized with automatism status in which the seizures(More)