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STEREOSELECTIVITIES IN THE COUPLING REACTION BETWEEN SILYTATED PYRIMIDINE BASES AND 1-HALO-2,3-DIDEOXYRIBOSE
Coupling reactions between 1-chloro-2,3-dideoxyribose and silylated pyrimidines have been examined from the point of stereoselectivity. When the reaction was carried out in chloroform, theExpand
One-step synthesis of heteroaromatic-fused pyrrolidines via cyclopropane ring-opening reaction: application to the PKCbeta inhibitor JTT-010.
TLDR
A ring-opening reaction of cyclopropanes with five-membered heteroaromatics having a leaving group at C(2) was found to provideheteroaromatic-fused pyrrolidines in one step to synthesis of the protein kinase C-beta inhibitor JTT-010. Expand
Short Synthesis of (3S,4R)- and (3R,4R)-3-Hydroxy-4-hydroxymethyl-4-butanolides, Two Lactones from Levoglucosenone.
Two lactones, (3S,4R)- and (3R,4R)-3-hydroxy-4-hydroxymethyl-4-butanolides, were easily and stereoselectively synthesized in good yield from levoglucosenoneExpand
Synthesis of D-Altrose via D-Altrosan from Levoglucosenone
The stereoselective reduction and cis-dihydroxylation of levoglucosenone (1,6-anhydro-3,4-dideoxy-β-D-glycero-hex-3-enopyranos-2-ulose), gave D-altrosan (1,6-anhydro-β-D-altropyranose), which couldExpand
Acceleration and Stabilization Techniques for the Levenberg-Marquardt Method
TLDR
A new LM method of damped Gauss-Newton (GN) type is introduced which satisfies both properties of global convergence and quadratic convergence by controlling Marquardt factor and can stabilize convergence numerically. Expand
Preparation of cobalt(III) and nickel(II) complexes having an alkyl long chain and their surface tension reducing abilities
Cobalt(III) and nickel(II) complexes having an alkyl long chain were newly prepared. The critical micelle concentration and surface tension-reducing ability largely depend on the length of theExpand
Synthesis of 1,6:3,4-Dianhydro-b-D-talopyranose from Levoglucosenone: Epoxidation of Olefin via trans-Iodoacetoxylation
Levoglucosenone (1,6-anhydro-3,4-dideoxy-β-D-glycero-hex-3-enopyranos-2-ulose, 1) was converted to give 1,6:3,4-dianhydro-β-D-talopyranose (8) in good yield through stereoselectiveExpand
Novel synthesis of phytosphingosine from levoglucosenone
Abstract Phytosphingosine, (2 S ,3 S ,4 R )-2-amino-1,3,4-octadecanetriol was prepared in 8.6% overall yield in 17 steps from levoglucosenone (1,6-anhydro-3,4-dideoxy-β- d - glyceroExpand
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