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  • Fengling Pu, Kenichi Mishima, +8 authors Michihiro Fujiwara
  • Medicine, Biology
  • Journal of pharmacological sciences
  • 2007
  • In order to determine the differential effects of flavonoids on cerebral ischemia, we investigated the effects of (-)-epigallocatechin gallate (EGCG), catechin, rutin, and quercetin on spatial memoryContinue Reading
  • Kazuhide Hayakawa, Kenichi Mishima, +9 authors Michihiro Fujiwara
  • Medicine
  • Journal of neurochemistry
  • 2007 (First Published: 1 September 2007)
  • We examined the neuroprotective mechanism of cannabidiol, non-psychoactive component of marijuana, on the infarction in a 4 h mouse middle cerebral artery (MCA) occlusion model in comparison withContinue Reading
  • Tomoaki Ikeda, Kenichi Mishima, Tetsuya Yoshikawa, Katsunori Iwasaki, Tsuyomu Ikenoue
  • Psychology, Medicine
  • Behavioural Brain Research
  • 2001 (First Published: 8 January 2001)
  • We examined four different learning and memory tasks in rats which had been subjected to left carotid artery ligation followed by 2 h hypoxia (8% oxygen) when they were 7 days old. The examinationContinue Reading
  • Nobuaki Egashira, Kenichi Mishima, Katsunori Iwasaki, Michihiro Fujiwara
  • Biology, Medicine
  • Brain Research
  • 2002 (First Published: 1 October 2002)
  • The purpose of this study was to identify brain sites that contribute to the delta(9)-tetrahydrocannabinol (delta(9)-THC)-induced impairment of spatial memory in rats. Rats were tested in theContinue Reading
  • Tetsuro Murakami, Erwan Paitel, +23 authors Mikio Shoji
  • Biology, Medicine
  • The American journal of pathology
  • 2006 (First Published: 1 October 2006)
  • Recapitulation of tau pathologies in an animal model has been a long-standing goal in neurodegenerative disease research. We generated transgenic (TgTauP301L) mice expressing a frontotemporalContinue Reading
  • Kazuhide Hayakawa, Takafumi Nakano, +8 authors Michihiro Fujiwara
  • Biology, Medicine
  • Journal of cerebral blood flow and metabolism…
  • 2010 (First Published: 1 April 2010)
  • Glial scarring is traditionally thought to be detrimental after stroke. But emerging studies now suggest that reactive astrocytes may also contribute to neurovascular remodeling. Here, we assessedContinue Reading