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The hepatitis temporal database collected at Chiba university hospital between 1982--2001 was recently given to challenge the KDD research. The database is large where each patient corresponds to 983 tests represented as sequences of irregular timestamp points with different lengths. This paper presents a temporal abstraction approach to mining knowledge(More)
OBJECTIVE The 2010 American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) classification criteria for rheumatoid arthritis (RA) refer to a possible use of ultrasound "for confirmation of the clinical findings." We undertook this study to determine the optimized definition of ultrasound-detected synovitis for the 2010 ACR/EULAR(More)
This paper proposes a novel decision tree for a data set with time-series attributes. Our time-series tree has a value (i.e. a time sequence) of a time-series attribute in its internal node, and splits examples based on dis-similarity between a pair of time sequences. Our method selects, for a split test, a time sequence which exists in data by exhaustive(More)
In this paper, we apply our PrototypeLines to Chronic Hepatitis Data and demonstrate the results so that domain experts can inspect them closely. PrototypeLines represents a method which visualizes irregular multi-dimensional time-series data as a sequence of probabilistic prototypes. It displays summarized information based on a proba-bilistic mixture(More)
More than 10 years ago Haux et al. tried to answer the question how health care provision will look like in the year 2013. A follow-up workshop was held in Braunschweig, Germany, for 2 days in May, 2013, with 20 invited international experts in biomedical and health informatics. Among other things it had the objectives to discuss the suggested goals and(More)
INTRODUCTION This study aimed to investigate the efficacy of abatacept for arthritis in patients with rhupus, an overlap syndrome between rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). METHODS Patients who fulfilled both the 2010 ACR/EULAR criteria for RA classification and the 1997 ACR revised criteria for classification of SLE and(More)
Worldwide populations are aging and countries have to prepare for the effects of demographic change in health care. Health information exchange (HIE), which is the process of moving patient information across health care providers electronically, can help overcome health data fragmentation and open opportunities to improve patient care in terms of quality,(More)
Health care and information technology in health care is advancing at tremendous speed. We analysed whether the prognoses by Haux et al. - first presented in 2000 and published in 2002 [1] - have been fulfilled in 2013 and which might be the reasons for match or mismatch. Twenty international experts in biomedical and health informatics met in May 2013 in a(More)
Systemic lupus erythematosus (SLE) is a multisystem, autoimmune, connective-tissue disorder with a broad range of clinical presentations. SLE predominantly affects women, especially from ethnic groups with African and Asian ancestry. This disorder is a chronic illness that can be life threatening when major organs are affected, but more commonly results in(More)