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Preconditioned suppression of prolyl-hydroxylases attenuates renal injury but increases mortality in septic murine models.
BACKGROUND Septic conditions contribute to tissue hypoxia, potentially leading to multiple organ failure, including acute kidney injury. The regulation of cellular adaptation to low oxygen levels isExpand
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MORG1+/− mice are protected from histological renal damage and inflammation in a murine model of endotoxemia
BackgroundThe MAPK-organizer 1 (MORG1) play a scaffold function in the MAPK and/or the PHD3 signalling paths. Recently, we reported that MORG1+/− mice are protected from renal injury induced byExpand
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Wild‐type FLT3 and FLT3 ITD exhibit similar ligand‐induced internalization characteristics
Class III receptor tyrosine kinases control the development of hematopoietic stem cells. Constitutive activation of FLT3 by internal tandem duplications (ITD) in the juxtamembrane domain has beenExpand
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Rolle der Prolyl-Hydroxylasen und des Renin-Aldosteron-Angiotensin-Systems bei sepsisinduzierter Nierenschädigung
Der Sepsis liegt in der Regel eine Infektion zugrunde, die zur systemisch-inflammatorischen Reaktion fuhrt und sich bei einer Dysfunktion des endogenen Abwehr- und Reparatursystems zu einer schwerenExpand
’ s response to reviews Title : MORG 1 + /-mice are protected from histological renal damage and inflammation in a murine model of endotoxemia
section, line 31, page 2; deleted “an”; Background section, line 82, page 4 localized was replaced by localised, As well also some spelling mistakes and the name of the city Dusseldorf are correctedExpand
Ramipril pretreatment worsened renal injury and survival despite a reduction in renal inflammation in experimentally induced sepsis in mice
Introduction: The angiotensin converting enzyme inhibitor ramipril is a standard antihypertensive therapy for many patients. Because angiotensin II may promote inflammation, we were interested inExpand
Cultural stereotypes as barriers to successful intercultural communication
Die kulturellen Werte, mit denen wir aufwachsen, sind so tief in uns verwurzelt, dass wir sie fur selbstverstandlich erachten oder uns so ihrer oft gar nicht bewusst sind. Allerdings kann dieExpand
Procédé de fabrication de structures périodiques sur une surface d'un substrat
La presente invention concerne un systeme et un procede de fabrication de structures periodiques sur une surface d'une tranche. En particulier, une surface de la tranche est revetue d'une reserveExpand