Katrin Saile

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Uterine leiomyomas (fibroids) are benign tumors that are prevalent in women of reproductive age. Research suggests that activated receptor tyrosine kinases (RTKs) play an important role in the enhanced proliferation observed in fibroids. In this study, a phospho-RTK array technique was used to detect RTK activity in leiomyomas compared with myometrial(More)
OBJECTIVE To determine if blood pressure measured with an ultrasonic Doppler flow detector (Doppler) is in good agreement with directly measured blood pressures in anesthetized cats. DESIGN Prospective observational study. SETTING University veterinary teaching hospital. ANIMALS Thirty-nine cats undergoing routine neutering. INTERVENTIONS Cats were(More)
OBJECTIVE To describe the clinical course, diagnostic findings, medical and surgical treatments, and outcome in a dog with spontaneous pneumothorax secondary to necrotizing pneumonia thought to be a delayed complication of heatstroke. CASE SUMMARY A 1.5-year-old Labrador Retriever developed spontaneous pneumothorax 12 days after an episode of exertional(More)
OBJECTIVE To assess the effects of sample size and location, skin tension lines, surgeon, and formalin fixation on the extent of shrinkage that occurs in excised canine skin samples. ANIMALS Cadavers of 4 adult purpose-bred mixed-breed hound dogs with grossly normal skin. PROCEDURES 54 circular areas of skin (2-, 4-, and 6-cm-diameter samples from each(More)
BACKGROUND Implantable cardioverter defibrillators (ICD) are programmed to detect ventricular arrhythmias and terminate them by delivering an electrical shock. A defibrillation threshold (DFT) at least 10 J below the maximum device output is recommended for successful therapy. Shock waveform configuration is a programmable parameter used to achieve a low(More)
OBJECTIVE To determine the volume of saline needed to achieve targeted intraluminal pressures during leak testing of closed jejunal biopsy sites in the dog. STUDY DESIGN Experimental. ANIMALS Dogs (n=38). METHODS Jejunal biopsies in dogs were performed and closed using 3-4 full thickness simple interrupted sutures. Saline volumes needed to achieve 2(More)
The acute abdomen is a challenging clinical problem that requires an early and accurate diagnosis in order to minimize patient morbidity and mortality. There are many definitions but key to most is that there is a sudden onset of severe abdominal pain that is less than 24 hours in duration. The challenge lies in determining if a patient is truly suffering(More)