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Detection of antinuclear antibodies by indirect immunofluorescence and by solid phase assay.
Testing for antinuclear antibodies is useful for the diagnosis of systemic rheumatic diseases. Solid phase assays are increasingly replacing indirect immunofluorescence for detection of antinuclearExpand
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Antinuclear antibody detection by automated multiplex immunoassay in untreated patients at the time of diagnosis.
Fully automated multiplex immunoassays are increasingly used as first line screening for antinuclear antibodies. The diagnostic performance of such multiplex assays in untreated patients at the timeExpand
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Antibodies to GP2, the major zymogen granule membrane glycoprotein, in inflammatory bowel diseases
It was with interest that we read the paper by Roggenbuck et al 1 in a recent issue of Gut , where GP2, the major zymogen granule membrane glycoprotein, is demonstrated to be the autoantigen ofExpand
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Heterogeneous nuclear RNPs as targets of autoantibodies in systemic rheumatic diseases.
OBJECTIVE To investigate the abundance of autoantibodies to heterogeneous nuclear RNPs (hnRNPs) in systemic rheumatic diseases. METHODS Recombinant human hnRNPs A1, B1, C1, E1, F, Gi, H1, I, K, andExpand
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Heterogeneous nuclear ribonucleoprotein h1, a novel nuclear autoantigen.
BACKGROUND Serum samples from patients with autoimmune connective tissue diseases that show a finely speckled antinuclear antibody (ANA) on indirect immune-fluorescence often have antibodies againstExpand
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Immune reactivity to β-tubulin isotype 5 and vesicular integral-membrane protein 36 in patients with autoimmune gastrointestinal disorders
It was with interest that we read the paper by Terjung et al 1, in a recent issue of Gut , where human myeloid cell-specific β-tubulin isotype 5 was identified as the target antigen of atypicalExpand
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