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OBJECTIVE To develop and assess a combined reading for contrast-enhanced magnetic resonance (CE-MRI) and diffusion weighted imaging (DWI) adapted to the BI-RADS for multiparametric MRI of the breast at 3 T. METHODS A total of 247 patients with histopathologically verified breast lesions were included in this IRB-approved prospective study. All patients(More)
PURPOSE To develop a 3.0 Tesla breast imaging protocol that combines high temporal and spatial resolution three-dimensional MR sequences for quantitative time course and morphologic analysis of breast lesions. MATERIALS AND METHODS Thirty-four patients were included in the study (age range, 31-82; mean age, 54.3). The study protocol was approved by the(More)
OBJECTIVES Sixty three healthy subjects were measured to assess dependence of brain metabolites on age using short- and long echo time spectroscopy in different brain regions. MATERIAL AND METHODS Younger and elderly humans were measured with long echo time (TE=135ms) 3D-MR-spectroscopic imaging (MRSI) (10 subjects) and with ultra-short echo (TE=11ms)(More)
PURPOSE To evaluate the diagnostic accuracy of quantitative, three-dimensional (3D) magnetic resonance (MR) spectroscopic imaging at 3 T for the differentiation of benign and malignant breast lesions, on the basis of choline (Cho) signal-to-noise ratio (SNR) threshold levels, in a clinically feasible measurement time. MATERIALS AND METHODS Institutional(More)
INTRODUCTION The purpose of this study was to compare the diagnostic accuracy of dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) as a single parameter to multiparametric (MP) MRI with 2 (DCE MRI and diffusion-weighted imaging [DWI]) and 3 (DCE MRI, DWI, and 3-dimensional proton magnetic resonance spectroscopic imaging [3D H-MRSI])(More)
PURPOSE To evaluate the image quality, robustness, and diagnostic performance of submillimeter in-plane resolution diffusion-weighted ( DW diffusion-weighted ) magnetic resonance (MR) imaging at 7 T in the assessment of breast tumors. MATERIALS AND METHODS Institutional review board approval and written informed consent of five volunteers and 33 patients(More)
OBJECTIVE To compare the diagnostic performance of full-field digital mammography (FFDM) with screen-film mammography (SFM) in a corporate screening programme including younger women. METHODS Data were available on 14,946 screening episodes, 5010 FFDM and 9936 SFM. Formal analysis was by logistic regression, adjusting for age and calendar year. FFDM is(More)
PURPOSE To demonstrate the feasibility of delayed gadolinium-enhanced magnetic resonance imaging (MRI) of cartilage (dGEMRIC) in the ankle at 3 T and to obtain preliminary data on matrix associated autologous chondrocyte (MACI) repair tissue. MATERIALS AND METHODS A 3D dual flip angle sequence was used with an eight-channel multipurpose coil at 3 T to(More)
OBJECTIVES The objective of this study was to compare the image quality, contrast enhancement behavior, and diagnostic value of bilateral 3-dimensional dynamic contrast-enhanced breast magnetic resonance imaging (MRI), with high spatial and temporal resolution, at 3 and 7 T, in the same patient group. MATERIALS AND METHODS Twenty-four consecutive patients(More)
INTRODUCTION To demonstrate intratumoral susceptibility effects in malignant brain tumors and to assess visualization of susceptibility effects before and after administration of the paramagnetic contrast agent MultiHance (gadobenate dimeglumine; Bracco Imaging), an agent known to have high relaxivity, with respect to susceptibility effects, image quality,(More)