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We report pregnancy outcome and fetal side effects in women at high risk of second trimester loss and early preterm delivery treated with nimesulide. This was a prospective observational study of 44 women treated with nimesulide from 17 to 32 weeks. All women underwent weekly ultrasound scans for AFI, Doppler studies of the ductus arteriosus and(More)
OBJECTIVES To assess if the clinical diagnosis of third degree tears could be improved by increased vigilance in perineal assessment. STUDY DESIGN A prospective observational study of all nulliparous vaginal deliveries sustaining perineal trauma (483) over a 6-month period at Queen Charlotte's Hospital. RESULTS A total of 121 women were independently(More)
  • Katie M Groom
  • 2007
The acute treatment of premature labour is successful for delaying delivery for short periods of time. Acute tocolysis does not have a significant impact on perinatal outcome. This is likely to be because the process leading to labour occurs over a longer timeframe and therefore therapies instigated as preventative measures are more likely to be successful(More)
Antenatal magnesium sulphate reduces the risk of cerebral palsy in babies born <30 weeks' gestation. A guideline for its use in women at imminent risk of preterm birth was implemented at National Women's Health, Auckland City Hospital in 2012. This prospective audit assessed adherence to the guideline in women delivering at <30 weeks in the first year after(More)
OBJECTIVES To describe changes in mean uterine artery resistance index and bilateral notches between 20 and 24 weeks of gestation in healthy nulliparous women and to relate these changes to pregnancy outcome. METHODS A total of 2,189 nulliparous participants in the Screening for Pregnancy Endpoints study had pregnancy outcomes compared between four(More)
BACKGROUND Increasing rates of postpartum haemorrhage in developed countries over the past two decades are not explained by corresponding changes in risk factors and conjecture has been raised that maternal obesity may be responsible. Few studies investigating risk factors for PPH have included BMI or investigated PPH risk among nulliparous women. The aim(More)
OBJECTIVE To compare pregnancy outcome for women at risk of preterm delivery undergoing elective cervical cerclage in the first trimester or serial transvaginal assessment of cervical length with cerclage only if indicated (control cases). DESIGN A matched case control study. SETTING Prematurity clinic at two London teaching hospitals. POPULATION(More)
OBJECTIVE To assess UK obstetricians' preferences about mode of delivery for themselves or their partners and determine whether these changed since 1995. STUDY DESIGN All 313 registered obstetricians in London and one in five (279) sample of those outside London were sent a structured anonymous postal questionnaire. RESULTS The response rate was 54%. In(More)
OBJECTIVES (1) To describe the association between small for gestational age (SGA) infants and pre-eclampsia (PE) and gestational hypertension (GH) and (2) to determine how this association changes with gestational age at delivery using customised centiles to classify infants as SGA. DESIGN A retrospective observational study. SETTING National Women's(More)