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Recently, we demonstrated that (+/-)-3,4-methylenedioxymethamphetamine (MDMA; ecstasy) was reliably and dose-dependently self-administered by previously drug-naïve laboratory rats. The neurochemical basis of MDMA self-administration has not, however, been extensively studied. The present study investigated the role of dopamine in MDMA self-administration(More)
Epidemiological and animal studies strongly indicate that the environment experienced in utero determines, in part, an individual's likelihood of developing cardiovascular disease in later life. This risk has been further linked to impaired kidney function, as a result of compromised development during fetal life. The present study therefore examined the(More)
N-benzylpiperazine (BZP) is the active ingredient in recreational 'party' or 'p.e.p.' pills, which are used to provide a stimulant, euphoric effect akin to that of methylenedioxymethamphetamine (MDMA, 'ecstasy'). BZP predominantly affects dopamine neurotransmission in a similar fashion to known 'drugs of abuse', such as methamphetamine and cocaine, which(More)
The mechanisms whereby maternal nutritional manipulation through pregnancy result in altered blood pressure in the offspring may include changes in fetal and newborn and adult renal prostaglandin (PG) synthesis, metabolism, and receptor expression. Since the postnatal effects of nutrient restriction on the renal PG synthesis and receptor system during(More)
  • Mary J. Arnoff, Amy Caryn Babb, +126 authors Patricia Mullinix
  • 2005
Abubakr, Saira Ahrens, Mary J. Arnoff, Amy Caryn Babb, Sheri Barr, Kimberly Barth, Monica L. Bastian, Anne Becker, Troy A. Bellcross, Cecelia A. Bellemore, Holly L. Berliner, Janice L. Berry, Debra Lynn Santillo Blachman, Tamara Bourguignon, Ann M. Bradburn, Joyce M. Braverman, Katie A. Brennan, Michele T. Brown, Stephanie A. Buehler, Elizabeth Ann(More)
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