Katia M. L. Charland

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BACKGROUND Rapid eye movement (REM) sleep behaviour disorder (RBD) is commonly associated with Parkinson's disease (PD), and recent studies have suggested that RBD in PD is associated with increased cognitive impairment, waking EEG slowing, autonomic impairment and lower quality of life on mental health components. However, it is unclear whether the(More)
OBJECTIVE Epidemiologic studies consistently link caffeine, a nonselective adenosine antagonist, to lower risk of Parkinson disease (PD). However, the symptomatic effects of caffeine in PD have not been adequately evaluated. METHODS We conducted a 6-week randomized controlled trial of caffeine in PD to assess effects upon daytime somnolence, motor(More)
OBJECTIVES There is a growing body of literature on malaria forecasting methods and the objective of our review is to identify and assess methods, including predictors, used to forecast malaria. DESIGN Scoping review. Two independent reviewers searched information sources, assessed studies for inclusion and extracted data from each study. INFORMATION(More)
BACKGROUND There is little empirical evidence in support of a relationship between rates of influenza infection and level of material deprivation (i.e., lack of access to goods and services) and social deprivation (i.e. lack of social cohesion and support). METHOD Using validated population-level indices of material and social deprivation and medical(More)
Syndromic surveillance is a novel automated approach to monitoring influenza activity, but there is no consensus regarding the most informative data sources for use within such a system. By comparing physician billing data from Quebec, Canada and hospital admission records, we assessed the timeliness of medical visits for influenza-like illnesses (ILI) to(More)
Malaria thrives in poor tropical and subtropical countries where local resources are limited. Accurate disease forecasts can provide public and clinical health services with the information needed to implement targeted approaches for malaria control that make effective use of limited resources. The objective of this study was to determine the relevance of(More)
It is generally challenging to obtain the exact disease prevalence, as the true cases of a disease in the population level are not easy to identify. Available and relevant data sources such as administrative or clinical health data are used in public health surveillance as a proxy to estimate the disease prevalence. Traditionally, these data sources span(More)
BACKGROUND Long-lasting insecticidal nets (LLINs) and indoor residual spraying of insecticide (IRS) are the primary vector control interventions used to prevent malaria in Africa. Although both interventions are effective in some settings, high-quality evidence is rarely available to evaluate their effectiveness following deployment by a national malaria(More)
and reproduction in any medium, provided the original work is properly cited. Objective We propose a simple statistical method, the cumulative case ratio, for defining a catchment area using surveillance data. Introduction The catchment area of a health-care facility is used to assess health service utilization and calculate population-based rates of(More)