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  • Ian E. Krop, Antonio C. Wolff, +7 authors Am. Storniolo
  • Medicine
  • 2010 (First Publication: 15 December 2010)
  • Background: Aberrant activation of the PI3K pathway has been hypothesized to reduce the efficacy of trastuzumab-based therapy in patients with HER2-positive breast cancer. Inhibition of the PI3KExpand
  • Mark Kozloff, George W. Sledge, +5 authors Kathy D. Miller
  • Medicine
  • 2010 (First Publication: 20 May 2010)
  • 2598 Background: Following debulking chemotherapy, tumor regrowth may rely on proliferation of a cellular subcompartment with progenitor cell or “stem cell”-like properties. Self-renewal of this stemExpand
  • Kathy D. Miller, Jorge E. Cortes, +9 authors Denise A. Yardley
  • Medicine
  • 2015 (First Publication: 20 May 2015)
  • TPS631Background: Although HER2-targeted therapies such as pertuzumab and T-DM1 have improved patient outcomes, treatment resistance typically occurs. MM-302 is a HER2-targeted liposomal doxorubicinExpand
  • Denise A. Yardley, Ahmad Awada, +8 authors Eric P. Winer
  • Medicine
  • 2014 (First Publication: 20 May 2014)
  • TPS653 Background: The androgen receptor (AR) is expressed in the majority of patients (pts) with ER/PgR+ breast cancer (BC)(Collins LC et al. Mod Pathol. 2011;24:924–931; Loibl S et al. BreastExpand
  • Catherine E. Mosher, Danielle Tometich, +10 authors Kathy D. Miller
  • Medicine
  • Psycho-oncology
  • 2017 (First Publication: 1 November 2017)
  • OBJECTIVE This study examined symptom-based subgroups of metastatic breast cancer (MBC) patients and the extent to which they differed across key constructs of acceptance and commitment therapyExpand
  • Andrew Dodson, Susan Parry, Merdol Ibrahim, John M. S. Bartlett, Mitchell Dowsett, Kathy D. Miller
  • Medicine
  • 2018 (First Publication: 15 February 2018)
  • AIMS To describe and analyse >168,000 sets of results from clinical breast biomarker testing carried-out between 2009 and 2016 in the UK and Republic of Ireland, focussing on biologicalExpand