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The gene for the cyclin‐dependent‐kinase‐4 inhibitor, CDKN2A, is preferentially deleted in malignant mesothelioma
Cytogenetic deletions of the short arm of chromosome 9, 9p, have been detected in cell lines of malignant mesothelioma as well as in tumor material. Many tumor types carry deletions of chromosome 9Expand
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PAX6 Mutations May Be Associated with High Myopia
PAX6 is a key regulator of eye development and there are many well recognized ophthalmic sequelae of mutations at this locus. The 14 exon PAX6 gene is well conserved across species and phyla. CodingExpand
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Expression of the wilms' tumor gene WT1 in human malignant mesothelioma cell lines and relationship to platelet‐derived growth factor A and insulin‐like growth factor 2 expression
Mutations in the WT1 tumor suppressor gene are known to contribute to the development of Wilms' tumor (WT) and associated gonadal abnormalities. WT1 is expressed principally in the fetal kidney,Expand
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Genetic interactions between the Wilms' tumor 1 gene and the p53 gene.
In recent years, a number of proteins have been identified that can modify the activities of the Wilms' Tumor 1 (WT1) proteins. One of these modifiers is the p53 protein. To investigate a geneticExpand
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Monoclonal antibodies to the NS protein of vesicular stomatitis virus inhibit initiation of transcripts in vitro and dissociate leader RNA from mRNA synthesis.
Three monoclonal antibodies directed against the NS protein of vesicular stomatitis virus inhibited homotypic in vitro transcription reactions. One antibody inhibited transcription only moderatelyExpand
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Genetic Interactions between the Wilms ’ Tumor 1 Gene and the p 53 Gene 1
In recent years, a number of proteins have been identified that can modify the activities of the Wilms’ Tumor 1 (WT1) proteins. One of these modifiers is the p53 protein. To investigate a geneticExpand