Kathryn Tworkoski

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Uterine cancer is the most common cancer of the female genital tract and is the fourth most frequent cause of cancer death in women in the U.S. Despite the high prevalence of uterine cancers, the molecular events that lead to neoplastic transformation in the uterus are poorly understood. Moreover, there are limited mouse models to study these malignancies.(More)
MicroRNAs (miRNAs) are small ∼22nt single stranded RNAs that negatively regulate protein expression by binding to partially complementary sequences in the 3' untranslated region (3' UTRs) of target gene messenger RNAs (mRNA). Recently, mutations have been identified in both miRNAs and target genes that disrupt regulatory relationships, contribute to(More)
In the 18th century, there was no standardized training for practitioners of medicine (or " physic(k), " as it was referred to at the time). The level of care sick individuals received was proportional to their social status, and diagnosis and treatment of illnesses varied widely between doctors. Medicine at Yale: The First 200 Years is the story of the(More)
broad series of topics ranging from communication issues with patients to helping physicians deal with psychological and ethical issues. Although it is aimed at health care providers who care for patients facing serious illnesses, it is a relevant resource for anyone who wants to learn more about pal-liative care. Overall, Care at the Close of Life is a(More)
With the growing popularity and acceptability of human embryonic stem cell research , an increasing number of researchers are looking for a way to break into the field and begin utilizing stem cells for their own work. Human Embryonic Stem Cells: The Practical Handbook is an invaluable resource for any such researcher and has plenty to offer experts in the(More)
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