Kathryn Tworkoski

Learn More
Uterine cancer is the most common cancer of the female genital tract and is the fourth most frequent cause of cancer death in women in the U.S. Despite the high prevalence of uterine cancers, the molecular events that lead to neoplastic transformation in the uterus are poorly understood. Moreover, there are limited mouse models to study these malignancies.(More)
In the 18th century, there was no standardized training for practitioners of medicine (or " physic(k), " as it was referred to at the time). The level of care sick individuals received was proportional to their social status, and diagnosis and treatment of illnesses varied widely between doctors. Medicine at Yale: The First 200 Years is the story of the(More)
UNLABELLED Epstein-Barr Virus (EBV) is a gammaherpesvirus that infects the majority of the human population and is linked to the development of multiple cancers, including nasopharyngeal carcinoma. Latent membrane protein 1 (LMP1) is considered the primary oncoprotein of EBV, and in epithelial cells it induces the expression and activation, or(More)
In our investigations of the bone marrow (BM) of PECAM-1 null (knockout, KO) mice, we observed that the trabecular bone volume and number of trabeculae were significantly reduced in femoral and tibial long bones. Further studies in vitro revealed increased numbers and size of osteoclasts, enhanced bone resorption on dentin substrates, and hypersensitivity(More)
broad series of topics ranging from communication issues with patients to helping physicians deal with psychological and ethical issues. Although it is aimed at health care providers who care for patients facing serious illnesses, it is a relevant resource for anyone who wants to learn more about palliative care. Overall, Care at the Close of Life is a very(More)
With the growing popularity and acceptability of human embryonic stem cell research, an increasing number of researchers are looking for a way to break into the field and begin utilizing stem cells for their own work. Human Embryonic Stem Cells: The Practical Handbook is an invaluable resource for any such researcher and has plenty to offer experts in the(More)
As the development of drugs continues to advance in the new decade, the development of molecular biomarkers must likewise advance in order to ensure that patients continue to receive the best possible standard of care. In Molecular Pathology in Drug Discovery and Development, editor J. Suso Platero argues that future medical care will need to be tailored to(More)
  • 1