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BACKGROUND Accurate estimates of multiple breath washout (MBW) outcomes require correct operation of the device, appropriate distraction of the subject to ensure they breathe in a manner… (More)
Introduction: Pulmonary inflammation, infection and structural lung disease occur early in life in children with CF leading to lung function decline. We aimed to determine if these markers of CF lung… (More)
Introduction: The lung clearance index (LCI) is a measure of ventilation inhomogeneity from the multiple breath washout test (MBW). In older children with CF, LCI is reported to have good agreement… (More)
The Progressive MS Alliance Industry Forum describes a new approach to address barriers to developing treatments for progressive multiple sclerosis (MS). This innovative model promises to facilitate… (More)
Polymicrobial infections of the respiratory tract due to antibiotic resistant bacteria are a great concern in patients with cystic fibrosis (CF). We therefore aimed at establishing a functional… (More)