Kathryn E. Richert-Boe

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BACKGROUND Prostate cancer is the second most common cause of death from cancer in men in the United States. Digital rectal examination is the oldest and most commonly used screening test for prostate cancer, but as yet there are no studies which demonstrate its effectiveness. METHODS A case-control study was conducted among members of a large health(More)
Objective: We performed a case–control study at Kaiser Permanente Northwest to assess the association between digital rectal examination (DRE) and prostate-specific antigen (PSA) testing, separately and together, and prostate cancer mortality. Methods: We identified 171 KPNW members who died as a result of prostate cancer from 1992 to 1999 and 342(More)
The purpose of this paper is to document the use of intravenous (IV) bisphosphonates for prevention of skeletal-related events (SREs) in patients with bone metastases (BM) due to breast cancer (BC), lung cancer (LC), or prostate cancer (PC). Using data from two large US health systems, we identified all patients aged ≥18 years with primary BC, LC, or PC and(More)
Prostate cancer has few known risk factors. As part of a population-based case–control study conducted in four health maintenance organizations, the authors examined the associations between fatal prostate cancer and several medical and behavioral characteristics. Cases were 768 health plan members who died of prostate adenocarcinoma during the period(More)
PURPOSE We determined the value of Decipher®, a genomic classifier, to predict prostate cancer outcomes among patients after prostatectomy in a community health care setting. MATERIALS AND METHODS We examined the experience of 224 men treated with radical prostatectomy from 1997 to 2009 at Kaiser Permanente Northwest, a large prepaid health plan in(More)
OBJECTIVES To determine whether differences existed in prostate cancer treatment received by white and African American men at a health maintenance organization where access to medical care is theoretically equal for all members and, if so, to determine the reasons for these differences. METHODS We used information from the Kaiser Permanente Northwest(More)
BACKGROUND AND METHODS To test the hypothesis that a "working conference" (WC; tumor board format in which any case requiring multispecialty input is presented for discussion) was preferable to a "fascinating case" (FC; only "interesting" or "unusual" cases presented) format, tumor board format at the Portland Veterans Affairs Medical Center was changed(More)
In 1954 a then 31-yr-old male was found to have erythrocytosis. Over the ensuing decade he received 72 mCi32P. In 1964 his daughters were found to have erythrocytosis. Further investigation led to the discovery of hemoglobin Yakima, a variant with high oxygen affinity. He received no further therapy and was well until 1975, when he developed the preleukemic(More)
BACKGROUND Gene fusions between the ERG transcription factor and the androgen-regulated gene TMPRSS2 occur in a subset of prostate cancers and contribute to transformation of prostatic epithelial cells. Prior reports have used fluorescence in situ hybridization (FISH) or quantitative PCR (QPCR) to determine the presence of TMPRSS2-ERG fusions or ERG(More)